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Aldosterone and type 2 diabetes mellitus

Hormone Molecular Biology and Clinical Investigation, 2016
Abstract Primary hyperaldosteronism (PA) has recently been demonstrated to be strictly associated to metabolic syndrome as compared with essential hypertension (EH). Besides, the characteristics of metabolic syndrome are different in PA compared to EH, as high fasting glucose is more frequent in the former condition.
Zavatta, Guido   +5 more
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Pathogenesis of type 2 diabetes mellitus

Medical Clinics of North America, 2004
This article provides an overview of the pathogenesis of type 2 diabetes mellitus. Discussion begins by describing normal glucose homeostasis and ingestion of a typical meal and then discusses glucose homeostasis in diabetes. Topics covered include insulin secretion in type 2 diabetes mellitus and insulin resistance, the site of insulin resistance, the
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Pharmacotherapy of Type 2 Diabetes Mellitus

The Annals of Pharmacotherapy, 2000
OBJECTIVE: To review the drug treatments and some of the popular, nontraditional remedies now available for type 2 diabetes mellitus, as well as selected investigational agents; to describe each medication's place in the overall approach to treatment. DATA SOURCES: English-language journals, abstracts, review articles, and newspaper accounts.
Marc Rendell, William R. Kirchain
openaire   +3 more sources

Exercise for type 2 diabetes mellitus

Cochrane Database of Systematic Reviews, 2006
Exercise is generally recommended for people with type 2 diabetes mellitus. However, some studies evaluate an exercise intervention including diet or behaviour modification or both, and the effects of diet and exercise are not differentiated. Some exercise studies involve low participant numbers, lacking power to show significant differences which may ...
Thomas, Diana   +2 more
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Pathogenesis of Type 2 Diabetes Mellitus

Archives of Medical Research, 2005
The pathological sequence for type 2 diabetes is complex and entails many different elements that act in concert to cause that disease. This review proposes a sequence of events and how they interact by a careful analysis of the human and animal model literature.
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Acatalasemia and type 2 diabetes mellitus

Orvosi Hetilap, 2015
The catalase enzyme decomposes the toxic concentrations of hydrogen peroxide into oxygen and water. Hydrogen peroxide is a highly reactive small molecule and its excessive concentration may cause significant damages to proteins, deoxyribonucleic acid, ribonucleic acid and lipids. Acatalasemia refers to inherited deficiency of the catalase enzyme.
László Góth   +2 more
openaire   +3 more sources

Genes and type 2 diabetes mellitus

Current Diabetes Reports, 2008
In 2007, five whole genome-wide association studies were published on the genetics of type 2 diabetes mellitus (T2DM), followed by the discovery of 11 genes consistently associated with T2DM. This breakthrough provided the first glimpses of a complete picture of the disease's genetic complexity.
Leif Groop, Valeriya Lyssenko
openaire   +3 more sources

Type 2 Diabetes Mellitus in Children

Endocrine Practice, 1998
To provide an overview of type 2 diabetes in children and discuss short-term and long-term management strategies.We review the distinction among various types of diabetes mellitus as they apply to children. In addition, we discuss determining the precise diagnosis between the two major variants--type 1 and type 2 diabetes--and clinical management of ...
John H. Pohl   +2 more
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Type 2 Diabetes Mellitus

1999
Type 2 diabetes mellitus is a disease characterized by both abnormalities in insulin secretion and target-tissue resistance to the actions of insulin. Therefore, it is not surprising that replacement therapy with insulin alone is not sufficient to control blood glucose and many of the other metabolic abnormalities in patients with type 2 diabetes ...
Rubin Bressler, David Johnson
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Lixisenatide for type 2 diabetes mellitus

Expert Opinion on Investigational Drugs, 2011
Type 2 diabetes mellitus (T2DM) is an increasing health problem worldwide. Glucagon-like peptide-1 (GLP-1) receptor agonists are an expanding drug class that target several of the pathophysiological traits of T2DM. Lixisenatide is a GLP-1 receptor agonist in development for once-daily treatment of T2DM.Pharmacological, preclinical and clinical evidence
Christensen, Mikkel   +3 more
openaire   +4 more sources

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