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Type 2 diabetes mellitus in adolescents
Current Opinion in Pediatrics, 2000Type 2 diabetes mellitus, a significant cause of adult morbidity and mortality, is being diagnosed more frequently in children and adolescents. Genetic predisposition and environmental factors are important determinants for the expression of this disease.
S T, Callahan, M J, Mansfield
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Hyperuricaemia and type 2 diabetes mellitus
Clinical and Experimental Pharmacology and Physiology, 2018SummaryChoi et al reported the effect of hyperuricaemia on the new‐onset type 2 diabetes mellitus (T2DM). I present three queries. (i) Insulin is considered to stimulate uric acid reabsorption via specific transporter and the effect of hyperuricaemia on the new‐onset T2DM should be evaluated by considering insulin resistance. (ii) There is a limitation
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Genes and type 2 diabetes mellitus
Current Diabetes Reports, 2008In 2007, five whole genome-wide association studies were published on the genetics of type 2 diabetes mellitus (T2DM), followed by the discovery of 11 genes consistently associated with T2DM. This breakthrough provided the first glimpses of a complete picture of the disease's genetic complexity.
Leif, Groop, Valeriya, Lyssenko
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Genetics of type 2 diabetes mellitus
Diabetes Research and Clinical Practice, 2005The clinical picture of type 2 diabetes mellitus (T2DM) is formed by impairment in insulin secretion and resistance to insulin action. As a result of intensive efforts of the scientists around the world mutations and polymorphisms in a number of genes were linked with monogenic and polygenic forms of T2DM.
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Pathogenesis of Type 2 Diabetes Mellitus
Archives of Medical Research, 2005The pathological sequence for type 2 diabetes is complex and entails many different elements that act in concert to cause that disease. This review proposes a sequence of events and how they interact by a careful analysis of the human and animal model literature.
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[Insulin and type 2 diabetes mellitus].
Therapeutische Umschau. Revue therapeutique, 2009Worldwide an increasing number of persons suffers from type 2 diabetes. Often treatment with oral hypoglycemic agents is not sufficient for adequate glycemic control and additional insulin treatment is necessary. Treatment with insulin is recommended if HbA1c levels below 7% cannot be achieved despite lifestyle measures and the proper use of oral ...
Lanker, Andrea Daniela +2 more
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Microvascular Dysfunction in Diabetes Mellitus and Cardiometabolic Disease
Endocrine Reviews, 2021William B Horton, Eugene J Barrett
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The burden and risks of emerging complications of diabetes mellitus
Nature Reviews Endocrinology, 2022Dunya Tomić +2 more
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Screening for Type 2 Diabetes Mellitus
Annals of Internal Medicine, 2015Shelley, Selph +2 more
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