Results 81 to 90 of about 1,682,882 (302)

Effect of Dapagliflozin on Atrial Fibrillation in Patients With Type 2 Diabetes Mellitus

Circulation, 2020
Supplemental Digital Content is available in the text. Background: Atrial fibrillation (AF) and atrial flutter (AFL) are associated with both diabetes mellitus and its related comorbidities, including hypertension, obesity, and heart failure (HF). SGLT2 (
Thomas A. Zelniker, M. Bonaca, Remo H M Furtado, Ofri Mosenzon, J. Kuder, S. Murphy, Deepak L. Bhatt, Lawrence A Leiter, D. McGuire, John P H Wilding, A. Budaj, R. Kiss, F. Padilla, I. Gause-Nilsson, A. Langkilde, I. Raz, M. Sabatine, S. Wiviott   +17 more
semanticscholar   +1 more source

Diabetes mellitus in patients with heart failure and effect modification of risk factors for short-term mortality: An observational study from the Registro Colombiano de Falla Cardíaca (RECOLFACA)

Biomédica: revista del Instituto Nacional de Salud
Introduction. Heart failure and type 2 diabetes mellitus are critical public health issues. Objective. To characterize the risk factors for mortality in patients with heart failure and type 2 diabetes mellitus from a large registry in Colombia and to ...
Luis Eduardo Echeverría, Clara Saldarriaga, Sebastián Campbell-Quintero, Lisbeth Natalia Morales-Rodríguez, Juan David López-Ponce de León, Andrés Felipe Buitrago, Erika Martínez-Carreño, Jorge Alberto Sandoval-Luna, Alexis Llamas, Gustavo Adolfo Moreno-Silgado, Julián Vanegas-Eljach, Nelson Eduardo Murillo-Benítez, Ricardo Gómez-Paláu, Alex Arnulfo Rivera-Toquica, Juan Esteban Gómez-Mesa, RECOLFACA research group   +15 more
doaj   +1 more source

Effect of Dapagliflozin on Heart Failure and Mortality in Type 2 Diabetes Mellitus.

Circulation, 2019
BACKGROUND In DECLARE-TIMI 58 (Dapagliflozin Effect on Cardiovascular Events-Thrombolysis in Myocardial Infarction 58), the sodium-glucose cotransporter 2 inhibitor dapagliflozin reduced the composite end point of cardiovascular death/hospitalization for
Eri Toda Kato, Michael G. Silverman, Ofri Mosenzon, Thomas A. Zelniker, A. Cahn, Remo H M Furtado, J. Kuder, S. Murphy, Deepak L. Bhatt, L. Leiter, D. McGuire, John P H Wilding, Marc P. Bonaca, C. Ruff, Akshay S. Desai, S. Goto, P. Johansson, I. Gause-Nilsson, P. Johanson, A. Langkilde, I. Raz, M. Sabatine, S. Wiviott   +22 more
semanticscholar   +1 more source

Common variants of the TCF7L2 gene are associated with increased risk of type 2 diabetes mellitus in a UK-resident South Asian population [PDF]

, 2008
Background Recent studies have implicated variants of the transcription factor 7-like 2 (TCF7L2) gene in genetic susceptibility to type 2 diabetes mellitus in several different populations. The aim of this study was to determine whether variants of this
A Helgason, Abigail C Britten, AH Barnett, Anthony H Barnett, C Zhang, CM Damcott, GR Chandak, J Paul O'Hare, J Wang, JC Barrett, JC Florez, JC Florez, JV van Vliet-Ostaptchouk, LJ Scott, M Ann Kelly, R Saxena, R Zhang, RJ Loos, S Cauchi, S Cauchi, S Mayans, SE Humphries, SF Grant, Simon D Rees, Srikanth Bellary, Sudhesh Kumar, The International HapMap Consortium, U Smith, WHO Consultation   +28 more
core   +6 more sources

Serum visfatin in type 2 diabetes mellitus

The Egyptian Journal of Internal Medicine, 2013
IntroductionObesity is commonly associated with insulin resistance and hyperinsulinemia and is the most important risk factor for type 2 diabetes. Visfatin is an adipokine that exerts insulin-mimetic effects that stimulate muscle and adipocyte glucose ...
Samiha A. Abd Rabo, Nagwa A. Mohammed, Somayh S. Eissa, Abeer A. Ali, Sahar M. Ismail, Reham S. Gad   +5 more
doaj   +1 more source

The anti-atherogenic effects of thiazolidinediones [PDF]

, 2007
The thiazolidinediones (TZDs) rosiglitazone (ROS) and pioglitazone (PIO) are insulin-sensitising agents widely used to treat patients with type 2 diabetes mellitus (T2DM). Thiazolidinediones significantly improve glycaemic control in diabetics by reduced
Honisett, Suzy, Komesaroff, Paul A, Stojanovska, Lily   +2 more
core  

A prospective cohort study in patients with type 2 diabetes mellitus for validation of biomarkers (PROVALID) –study design and baseline characteristics [PDF]

, 2018
Background/Aims: The prevalence of diabetes mellitus type 2 and kidney disease in these patients varies widely between European countries. Methods: In addition to store biosamples the “Prospective cohort study in patients with type 2 diabetes mellitus ...
de Zeeuw, Dick, Eder, Susanne, Heerspink, Hiddo L., Heinze, Georg, Kerschbaum, Julia, Leierer, Johannes, Mark, Patrick B., Mayer, Gert, Rosivall, Laszlo, Rossing, Peter, Wiecek, Andrzej   +10 more
core   +6 more sources

TYPE 2 DIABETES MELLITUS;

The Professional Medical Journal, 2019
Background: Diabetic complications are related to impaired glycemic control. The UK Prospective Diabetes Study (UKPDS) showed that metformin therapy in overweight and obese patients with type 2 diabetes mellitus (T2DM) could reduce HbA1c and complications.
Masood Javed, Muzzammal Iftikhar, Dilshad Muhammad   +2 more
openaire   +2 more sources

Heart Failure in Type 2 Diabetes Mellitus.

Circulation Research, 2019
Patients with diabetes mellitus have >2× the risk for developing heart failure (HF; HF with reduced ejection fraction and HF with preserved ejection fraction).
H. Kenny, E. Abel
semanticscholar   +1 more source

Elevated Serum TNF-α Is Related to Obesity in Type 2 Diabetes Mellitus and Is Associated with Glycemic Control and Insulin Resistance

Journal of Obesity, 2020
Background Diabetes and obesity are very common associated metabolic disorders that are linked to chronic inflammation. Leptin is one of the important adipokines released from adipocytes, and its level increases with increasing body mass index (BMI ...
H. Alzamil
semanticscholar   +1 more source