Results 171 to 180 of about 2,069,243 (304)

Type 2 inflammation in chronic obstructive pulmonary disease: A promising treatable trait and practice recommendations. [PDF]

Chin Med J Pulm Crit Care Med
Chen Y, Yang T, Zhang J, Chen X, Chen X, Cheng Z, Li Y, Fan X, Han W, He Z, Ma D, Meng Y, Yan J, Yin Y, Zeng H, Zhou Q, Zhou X, Cai H, Cui Y, Ma Y, Wen F, Sun Y, Sun D, Liu X, Zheng J, Wang W, Zheng Z, Yan X, Cai S, Cao J, Song Y, Zhao J, Zhou Y, Zhu H, Li M, Guo Y, Ma Q, Liang Z, Zhao L, Chen Y, Wang J, Wang F, Yang Y, Yang H, Kang J, Chen R, Assembly of Chronic Obstructive Pulmonary Disease (COPD) of Chinese Thoracic Society (CTS), COPD Working Group of Chinese Association of Chest Physician (CACP) of the Chinese Medical Doctor Association, Evidence-Based Medicine Group of the Clinical Epidemiology Branch of the Chinese Medical Association, Respiratory Disease Control Committee of the Chinese Preventive Medicine Association, Precision Medicine Group of the Respiratory Disease Committee of the Cross-Strait Medical and Health Exchange Association.   +50 more
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Baseline Membrane Thickness in Asthma: Where Type-2 Inflammation Meets Remodeling? [PDF]

Am J Respir Crit Care Med
Melhorn J, Couillard S.
europepmc   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

The Burden of COPD with Type 2 Inflammation in North-West Continental Europe. [PDF]

Int J Chron Obstruct Pulmon Dis
Sandelowsky H, Løkke A, Kocks JWH, Grøttum HS, Bakke PS, Vasankari T.   +5 more
europepmc   +1 more source

Inflammation in Type 2 Diabetes [PDF]

, 2016
openaire   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

FeNO as a Non-Invasive Biomarker of Type 2 Inflammation in Chronic Rhinosinusitis with Nasal Polyps: Correlation with Serum IgE and Eosinophils. [PDF]

Iran J Otorhinolaryngol
Fereydouni S, Jabbari-Azad F, Bakhshaee M, Khoshkhui M, Yadegari Y, Mohammadi M.   +5 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Impact of Effect Modification of Type 2 Inflammation and Sex on Asthma Exacerbation Rates. [PDF]

CHEST Pulm
Agarwal T, Peterson R, Jimenez G, Taich Z, Sharma S, Holguin F, Althoff MD.   +6 more
europepmc   +1 more source