Results 201 to 210 of about 9,306,420 (267)

Further investigation of the impact of foveal and parafoveal word frequency on parafoveal preview during Chinese reading. [PDF]

PLoS One
Sun Y, Li S, Zhang Y, Wang J.
europepmc   +1 more source

A new attention-based deep metric model for crop type mapping in complex agricultural landscapes using multisource remote sensing data

Yizhen Zheng, Wen Dong, ZhipingYang, Yihang Lu, Xin Zhang, Yanni Dong, Fengqing Sun   +6 more
openalex   +1 more source

Development in Myxococcus xanthus involves differentiation into two cell types, peripheral rods and spores

, 1991
Kathleen O’Connor, David R. Zusman
openalex   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Cell type composition in bulk prostate cancer tissue is a prognostic biomarker. [PDF]

Neoplasia
Zhang X, Johannessen B, Kidd SG, Bogaard M, Stranger A, Axcrona U, Axcrona K, Skotheim RI.   +7 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Growth Plate Injury Leading to Madelung-Type Deformity After ESIN in Children: A Case Report and a Narrative Review of the Literature. [PDF]

Clin Case Rep
Cosentino A, Odorizzi G, Berger W.
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

The role of obesity and Type 2 diabetes in lung health: A systematic review (2024). [PDF]

PLoS One
Lecky R, Grogan S, Shukla P, Atkinson S, McClean PL, Kelly C.   +5 more
europepmc   +1 more source