Results 201 to 210 of about 23,120,603 (244)

Development of a Purple-Leaf Perillene Chemotype Line in <i>Perilla frutescens</i> Reveals Incomplete Linkage with Leaf Color. [PDF]

Plants (Basel)
Wei W, Wang B, Li Z, Liu Y, Ji H, Wu Z, Ma G, Sun Y, Zhang T, Liu Y, Feng L, Jin Y, Wang T, Wang Q, Gao Z, Wei J.   +15 more
europepmc   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Contrasting roles for IKK-regulated inflammatory signalling pathways for development and maintenance of type 1 and adaptive γδ T cells. [PDF]

Elife
Islam F, Williams C, Hogan T, Webb LV, Boal-Carvalho I, Seddon B.   +5 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Plain Language Summary of a Phase 2 Study of Triamcinolone Acetonide Extended-Release for Pain Relief in People With Knee Osteoarthritis and Type 2 Diabetes. [PDF]

Ther Adv Musculoskelet Dis
Spitzer AI, Rodbard H.
europepmc   +1 more source

Checkpoint blockade and the stem‐like T cell trade‐off

Molecular Oncology, EarlyView.
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley   +1 more source

A tale of dual role: HECT‑type E3 ubiquitin ligase mechanisms in liver diseases (Review). [PDF]

Int J Mol Med
Li T, Chen H, Zhao P, Yin C, Song Z.
europepmc   +1 more source

Aerobic exercise reduces oxidative damage and improves heart function in diabetic rats with heart failure: No extra effect from photobiomodulation. [PDF]

J Diabetes Metab Disord
Scherer NHB, Bahr AC, Capalonga L, Dorneles GP, Dal Lago P.   +4 more
europepmc   +1 more source