Results 221 to 230 of about 15,925,070 (360)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Regioselective rapid ene-type reaction (RRER) enables bioconjugation of histone serotonylation. [PDF]

RSC Chem Biol
Wu J, Li H, Lovato AR, Symasek A, Lin Z, Zheng Q.   +5 more
europepmc   +1 more source

Impact of temperature and prey type on biology and life-table parameters of Cheyletus malaccensis Oudemans (Acari: Cheyletidae)

, 2022
Ashraf Elhalawany, Hosnia A. Afifi, Eman L. Ayad   +2 more
openalex   +1 more source

Creatine metabolism: energy homeostasis, immunity and cancer biology

Nature Reviews Endocrinology, 2020
L. Kazak, P. Cohen
semanticscholar   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Analysis of disease resistance of ZmERS4 -overexpressing rice. [PDF]

PLoS One
Huang W, Ning J, Su B, Liu W, Ding T.
europepmc   +1 more source

On a new type of catastrophist representation for modelisation in biology and cognitive sciences

, 1997
Philippe Lacorre
openalex   +1 more source

New form of China aster (Callistephus chinensis (L.) Nees). Structure and biology of ray florets with open tubular corollas (type RO)

, 2013
Alicja Wosińska
openalex   +2 more sources

A biology-driven deep generative model for cell-type annotation in cytometry

, 2023
Quentin Blampey, Nadège Bercovici, Charles‐Antoine Dutertre, Isabelle Pic, Joana Ribeiro, Fabrice André, Paul-Henry Cournède   +6 more
openalex   +2 more sources

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source