Results 241 to 250 of about 15,925,070 (360)

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Single cell transcriptomic analysis reveals transcriptome differences of different cells between eosinophilic chronic rhinosinusitis with nasal polyps and non-eosinophilic chronic rhinosinusitis with nasal polyps. [PDF]

PLoS One
Jin Y, Liang Y, Wang Z, Jiang Y, Yuan F, Zhang T.   +5 more
europepmc   +1 more source

The Utilization of Various Plant Type by the Community of Gunung Bunder Dua Village, Bogor Regency as a Resource of Biology Learning Process

, 2020
Rizna Akmaliyah, Wardah Wardah, Tri Cahyanto, Apriani Krisdianti, Deasy Rahmawati   +4 more
openalex   +2 more sources

Supplementary Data for Newman JRB, Long A, Speake C, Greenbaum CJ, Cerosaletti K, Rich SS, Onengut-Gumuscu S, McIntyre LM, Buckner JH, Concannon P, "Shifts in isoform usage underlie transcriptional differences in regulatory T cells in type 1 diabetes", submitted to Communications Biology

, 2023
Jeremy R. B. Newman, Alice Long, Cate Speake, Carla J. Greenbaum, Karen Cerosaletti, Stephen S. Rich, Suna Onengut-Gomuscu, Lauren M. McIntyre, Patrick Concannon   +8 more
openalex   +2 more sources

Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

Nature Reviews Neurology, 2018
S. Arnold, Z. Arvanitakis, Shannon L. Macauley-Rambach, A. Koenig, Hoau Yan Wang, R. Ahima, S. Craft, S. Gandy, C. Buettner, L. Stoeckel, D. Holtzman, D. Nathan   +11 more
semanticscholar   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Cuticular collagens mediate cross-kingdom predator-prey interactions between trapping fungi and nematodes. [PDF]

PLoS Biol
Chang HW, Lin HC, Yang CT, Tay RJ, Chang DM, Tung YC, Hsueh YP.   +6 more
europepmc   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

Molecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci, Izzet Akiva, Yavuz Hakan Ozon, Hakan Berkil, Huseyin Karadayi, Omer Dizdar, Suayib Yalcin   +6 more
wiley   +1 more source

Pattern recognition in living cells through the lens of machine learning. [PDF]

Open Biol
Britto Bisso F, Aguilar R, Shree D, Zhu Y, Espinoza M, Diaz B, Cuba Samaniego C.   +6 more
europepmc   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source