Results 261 to 270 of about 15,878,608 (386)

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

Molecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar, Shima Shahbaz, Anthea C. Peters, Spencer B. Gibson, Shokrollah Elahi   +4 more
wiley   +1 more source

A 3D morpho-space of sepal geometry reveals the importance of organ curvature. [PDF]

Quant Plant Biol
Battu V, Kiss A, Delgado-Vaquera A, Sénéchal F, Mollier C, Hartasánchez DA, Boudaoud A, Monéger F.   +7 more
europepmc   +1 more source

A biology-driven deep generative model for cell-type annotation in cytometry

, 2023
Quentin Blampey, Nadège Bercovici, Charles‐Antoine Dutertre, Isabelle Pic, Joana Ribeiro, Fabrice André, Paul-Henry Cournède   +6 more
openalex   +2 more sources

Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

Nature Reviews Neurology, 2018
S. Arnold, Z. Arvanitakis, Shannon L. Macauley-Rambach, A. Koenig, Hoau Yan Wang, R. Ahima, S. Craft, S. Gandy, C. Buettner, L. Stoeckel, D. Holtzman, D. Nathan   +11 more
semanticscholar   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

An introductory overview of new article type “Opinion” in Plant Nano Biology

, 2023
Durgesh Kumar Tripathi
openalex   +1 more source

Editorial Overview: “Islet Biology in Type 2 Diabetes”

Journal of Molecular Biology, 2020
Gaisano, Herbert Y., Jonas, Jean-Christophe, Gloyn, Anna L.   +2 more
openaire   +4 more sources

Lipid droplets and liver disease: from basic biology to clinical implications

Nature Reviews Gastroenterology &Hepatology, 2017
N. Gluchowski, Michel Becuwe, T. Walther, Robert V Farese   +3 more
semanticscholar   +1 more source

Creatine metabolism: energy homeostasis, immunity and cancer biology

Nature Reviews Endocrinology, 2020
L. Kazak, P. Cohen
semanticscholar   +1 more source

TRPM4 contributes to cell death in prostate cancer tumor spheroids, and to extravasation and metastasis in a zebrafish xenograft model system

Molecular Oncology, EarlyView.
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen, Saurav Subedi, Federico La Manna, Sofia Jarrin, Irida Papapostolou, Marianna Kruithof‐de Julio, Christine Peinelt   +6 more
wiley   +1 more source