Results 71 to 80 of about 2,206,481 (294)

An insight into the genome of extensively drug-resistant and uropathogenic Citrobacter werkmanii

Journal of Global Antimicrobial Resistance, 2020
Objective: Carbapenemase-producing bacteria pose a serious public-health threat. This study was performed to understand the emergence and genetic features of NDM-producers in hospital setting. Methods: Samples were collected from a tertiary-care hospital.
Shadab Parvez, Ph.D., Asad U. Khan, Gurwinder Kaur, Mohamed Barakat, Philippe Ortet, Shanmugam Mayilraj   +5 more
doaj  

The emerging role of targeting cancer metabolism for cancer therapy

Tumor Biology, 2020
Glucose, as the main consuming nutrient of the body, faces different destinies in cancer cells. Glycolysis, oxidative phosphorylation, and pentose phosphate pathways produce different glucose-derived metabolites and thus affect cells’ bioenergetics ...
Pegah Farhadi, Reza Yarani, Sadat Dokaneheifard, Kamran Mansouri   +3 more
doaj   +1 more source

Loop Quantum Theory Applied to Biology and Nonlinear Whole Biology [PDF]

arXiv, 2008
The loop quantum theory, which constitutes a very small discontinuous space, as new method is applied to biology. The model of protein folding and lungs is proposed. In the model, some known results are used, and four approximate conclusions are obtained: their structures are quantized, their space regions are finite, various singularities correspond ...
arxiv  

Event based text mining for integrated network construction [PDF]

, 2010
The scientific literature is a rich and challenging data source for research in systems biology, providing numerous interactions between biological entities.
Saeys, Yvan, Van de Peer, Yves, Van Landeghem, Sofie   +2 more
core   +1 more source

Schmallenberg virus pathogenesis, tropism and interaction with the innate immune system of the host [PDF]

, 2013
Schmallenberg virus (SBV) is an emerging orthobunyavirus of ruminants associated with outbreaks of congenital malformations in aborted and stillborn animals.
A Bridgen, A Bridgen, A Kohl, AC Lowen, AJ Della-Porta, Alain Kohl, Andrew Shaw, Anna Janowicz, AR Elbers, B Hoffmann, B Xu, CA Evans, Catherine Lamm, Claudio Murgia, CM Southam, CT Walter, D Thomas, DH Cybinski, Esther Schnettler, Eva McGregor, F Arnaud, Friedemann Weber, G Barry, G Blakqori, G Blakqori, G Neumann, Gerald Barry, Ilaria M. Piras, JI Gillespie, JL Farmer, K Kupferschmidt, K Peperkamp, K Terasaki, K Wernike, KE Jones, Kerstin Hahn, KV Goller, LD Rasmussen, M Beer, M Bouloy, M Caporale, M Dominguez, M Palmarini, M Ratinier, M Spiegel, M Varela, Mandy Glass, Marco Caporale, Mariana Varela, Martin Beer, Massimo Palmarini, Melanie McFarlane, MJ Killip, MM Garigliany, MM Garigliany, NR Saunders, OR Causey, P Vialat, PJ Hotez, PT Leisnham, R Muller, RS Azevedo, S Shimshony, SE Randolph, T Ikegami, T Yanase, UJ Buchholz, V Herder, Vanessa Herder, VH Leonard, Wolfgang Baumgärtner, X Shi, Y Ogawa, YK Liao   +73 more
core   +3 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Regulatory T cells in the mouse hypothalamus control immune activation and ameliorate metabolic impairments in high-calorie environments

Nature Communications
The hypothalamus in the central nervous system (CNS) has important functions in controlling systemic metabolism. A calorie-rich diet triggers CNS immune activation, impairing metabolic control and promoting obesity and Type 2 Diabetes (T2D), but the ...
Maike Becker, Stefanie Kälin, Anne H. Neubig, Michael Lauber, Daria Opaleva, Hannah Hipp, Victoria K. Salb, Verena B. Ott, Beata Legutko, Roland E. Kälin, Markus Hippich, Martin G. Scherm, Lucas F. R. Nascimento, Isabelle Serr, Fabian Hosp, Alexei Nikolaev, Alma Mohebiany, Martin Krueger, Bianca Flachmeyer, Michael W. Pfaffl, Bettina Haase, Chun-Xia Yi, Sarah Dietzen, Tobias Bopp, Stephen C. Woods, Ari Waisman, Benno Weigmann, Matthias Mann, Matthias H. Tschöp, Carolin Daniel   +29 more
doaj   +1 more source

Odour-mediated orientation of beetles is influenced by age, sex and morph [PDF]

, 2012
The behaviour of insects is dictated by a combination of factors and may vary considerably between individuals, but small insects are often considered en masse and thus these differences can be overlooked.
A Salisbury, AJ Mossi, C Kestenholz, CW Fox, DA Ukeh, DT Nguyen, EA Elhag, ET Zannou, FJ Messina, FJ Messina, FJ Messina, FJ Messina, Frederic Marion-Poll, GH Caswell, HCF Su, HT Al-Lawati, I Sano-Fujii, I Sano-Fujii, J Hardie, J Jaba, J Kamanula, J Pickett, J Zhu, JC Dickens, JM van der Meer, JO Gendo, LK Miller, LPJJ Noldus, LR Hallsson, LR Hallsson, LS Nerio, MS Nahdy, P Lextrait, P Trematerra, PA Mackay, Philip C. Stevenson, RG Harrison, S Belmain, S Ignacimuthu, S Utida, S Williamson, SA Budick, Sarah E. J. Arnold, SJ Boeke, SJ Boeke, SJ Torr, Steven R. Belmain, T Bashir, TK Jayasekara, TK Jayasekara, Y-J Du   +50 more
core   +2 more sources

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

Life as Complex Systems --- Viewpoint from Intra-Inter Dynamics [PDF]

arXiv, 1998
Basic problems in complex systems are surveyed in connection with Life. As a key issue for complex systems, complementarity between syntax/rule/parts and semantics/behavior/whole is stressed. To address the issue, a constructive approach for a biological system is proposed.
arxiv