Results 71 to 80 of about 15,925,070 (360)
Exosomal lipid composition and the role of ether lipids and phosphoinositides in exosome biology
Journal of Lipid Research, 2018 Exosomes are a type of extracellular vesicle released from cells after fusion of multivesicular bodies with the plasma membrane. These vesicles are often enriched in cholesterol, SM, glycosphingolipids, and phosphatidylserine.
T. Skotland +3 more
semanticscholar +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Event based text mining for integrated network construction [PDF]
, 2010 The scientific literature is a rich and challenging data source for research in systems biology, providing numerous interactions between biological entities.
Saeys, Yvan +2 more
core +1 more source
Botulinum Neurotoxins: Biology, Pharmacology, and Toxicology
Pharmacological Reviews, 2017 The study of botulinum neurotoxins (BoNT) is rapidly progressing in many aspects. Novel BoNTs are being discovered owing to next generation sequencing, but their biologic and pharmacological properties remain largely unknown.
M. Pirazzini +3 more
semanticscholar +1 more source
Coronavirus infections and type 2 diabetes-shared pathways with therapeutic implications
Endocrine reviews, 2020 Individuals with diabetes are at increased risk for bacterial, mycotic, parasitic and viral infections. The severe acute respiratory syndrome (SARS)-CoV2 (also referred to as COVID-19) coronavirus pandemic highlights the importance of understanding ...
D. Drucker
semanticscholar +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Variation in some characters of the genus Sceliphron (Hymenoptera: Sphecidae) in the Philippines
Journal of Asia-Pacific Biodiversity, 2020 The observed morphological and color variations for Sceliphron species in the Philippines are hereby reported. Sceliphron madraspatanum conspicillatum and Sceliphron rufopictum laticinctum have several variations in propodeal maculation pattern and in ...
Kristine O. Abenis +3 more
doaj
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Type 2 diabetes, mitochondrial biology and the heart [PDF]
Journal of Molecular and Cellular Cardiology, 2009 Diabetes is recognized as an independent risk factor for cardiovascular morbidity and mortality. This is due, in large part, to premature atherosclerosis, enhanced thrombogenicity and activation of systemic inflammatory programs with resultant vascular dysfunction.
openaire +3 more sources
Journal of experimental & clinical cancer research : CR, 2019 The extracellular matrix (ECM) plays an important role in cancer progression. It can be divided into the basement membrane (BM) that supports epithelial/endothelial cell behavior and the interstitial matrix (IM) that supports the underlying stromal ...
N. Nissen, M. Karsdal, N. Willumsen
semanticscholar +1 more source