Results 11 to 20 of about 400,595 (267)
Current Insights into Collagen Type I [PDF]
Polymers, 2021 Collagen type I (Col-I) is unique due to its high biocompatibility in human tissue. Despite its availability from various sources, Col-I naturally mimics the extracellular matrix (ECM) and generally makes up the larger protein component (90%) in vasculature, skin, tendon bone, and other tissue.
Ruth Naomi +2 more
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Nanomechanics of Type I Collagen [PDF]
Biophysical Journal, 2016 Type I collagen is the predominant collagen in mature tendons and ligaments, where it gives them their load-bearing mechanical properties. Fibrils of type I collagen are formed by the packing of polypeptide triple helices. Higher-order structures like fibril bundles and fibers are assembled from fibrils in the presence of other collagenous molecules ...
Sameer, Varma +2 more
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Toxins, 2023 Consumption coagulopathy and hemorrhagic syndrome exacerbated by blood anticoagulability remain the most important causes of lethality associated with Bothrops snake envenomation.
Olivier Pierre-Louis +7 more
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Interaction of Biglycan with Type I Collagen [PDF]
Journal of Biological Chemistry, 1995 The small proteoglycan decorin is known to interact with type I collagen fibrils, thereby influencing the kinetics of fibril formation and the distance between adjacent collagen fibrils. The structurally related proteoglycan biglycan has been proposed not to bind to fibrillar collagens.
E, Schönherr +5 more
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Biochemical markers of bone collagen type I metabolism [PDF]
The Ukrainian Biochemical Journal, 2015 This review focuses on the analysis of diagnostic value of the major bone remodeling markers, in particular synthesis and degradation markers of collagen type I.
O. V. Zaitseva +2 more
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Scientific Reports, 2022 Intrahepatic cholangiocarcinoma (iCCA) arises along the peripheral bile ducts and is often accompanied by a tumor microenvironment (TME) high in extracellular matrices (ECMs).
Chotirat Rattanasinchai +2 more
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Mineralization of Type I Collagen [PDF]
Biophysical Journal, 2003 It was previously found that the lateral spacing of the collagen molecules in wet mineralized tissues is exactly proportional to the inverse wet density. Several properties were investigated and the same type of relationship was observed each time. A possible explanation is offered.
openaire +2 more sources
Lung collagens perpetuate pulmonary fibrosis via CD204 and M2 macrophage activation. [PDF]
PLoS ONE, 2013 Idiopathic pulmonary fibrosis is characterized by abundant collagen production and accumulation of alternatively activated macrophages (M2) in the lower respiratory tract.
Mirjam Stahl +6 more
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Cells, 2022 Idiopathic pulmonary fibrosis is a chronic intractable lung disease, leading to respiratory failure and death. Although anti-fibrotic agents delay disease progression, they are not considered curative treatments, and alternative modalities have attracted
Daisuke Okuno +11 more
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Thoracic Cancer, 2019 Background Extracellular matrix (ECM) is remodeled during carcinogenesis. An abundant constituent of ECM is collagen. Type I collagen is secreted by fibroblasts, is important for tumor growth and epithelial‐mesenchymal transition, and may also be ...
Shuo Fang +7 more
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