Results 11 to 20 of about 387,781 (267)

Effect of Low-Temperature Plasma Jet on Thermal Stability and Physical Structure of Type I Collagen [PDF]

, 2012
This work is devoted to the characterization of type I collagen treated by a low-temperature plasma jet generated in ambient air to determine whether the resulting fibrous material is structurally preserved or reinforced.
Yousfi, Mohammed, Gardou, Jean-Pierre, Merbahi, Nofel, Delaunay, Florian, Lacabanne, Colette, Samouillan, Valérie, Dandurand, Jany   +6 more
core   +1 more source

ER stress-mediated apoptosis in a new mouse model of osteogenesis imperfecta [PDF]

, 2008
Osteogenesis imperfecta is an inherited disorder characterized by increased bone fragility, fractures, and osteoporosis, and most cases are caused by mutations affecting the type I collagen genes.
Ralston, Stuart H., Thomas S Lisse, Eckhard Wolf, Quintanilla-Martinez Leticia, de Angelis Martin Hrabé, Fuchs Helmut, Lisse Thomas S, Gabriele Hoelzlwimmer, Hrabě de Angelis, M., Martin Hrabé de Angelis, Hölzlwimmer, G., Abe, Koichiro, Rathkolb, Birgit, de Angelis, Martin Hrabe, Hans, Wolfgang, Rathkolb, B., Quintanilla-Martinez, Leticia, Ralston, Stuart H, Koichiro Abe, Abe, K., Wolf Eckhard, Przemeck, G.K.H., Hans Wolfgang, Hoelzlwimmer, Gabriele, Przemeck Gerhard K. H, Fuchs, H., Abe Koichiro, Hoelzlwimmer Gabriele, Hrabé de Angelis, Martin, Wolf, E., Miep Helfrich, Lisse, Thomas S, Quintanilla-Martinez, L., Thiele, F., Ralston, S.H., Helmut Fuchs, Gerhard K H Przemeck, Helfrich, M., Helfrich, Miep, Przemeck, Gerhard K. H., Lisse, Thomas S., Thiele, Frank, Frank Thiele, Helfrich Miep, Stuart H Ralston, Wolfgang Hans, Hans, W., Przemeck, Gerhard K H, Thiele Frank, Rathkolb Birgit, Ralston Stuart H, Lisse, T.S., Birgit Rathkolb, Fuchs, Helmut, Wolf, Eckhard, Leticia Quintanilla-Martinez   +55 more
core   +1 more source

A biomimetic model for mineralization of type-I collagen fibrils [PDF]

, 2019
The bone and dentin mainly consist of type-I collagen fibrils mineralized by hydroxyapatite (HAP) nanocrystals. In vitro biomimetic models based on self-assembled collagen fibrils have been widely used in studying the mineralization mechanism of type-I ...
Nudelman, Fabio, Ruikang Tang, Yifei Xu, Shao, Changyu, Sommerdijk, Nico A.J.M., Changyu Shao, Fabio Nudelman, Afratis, Nikolaos A., Nico A. J. M. Sommerdijk, Sagi, Irit, Tang, Ruikang, Yao, Shasha, Xu, Yifei, Shasha Yao, Sommerdijk, Nico A. J. M.   +14 more
core   +1 more source

Topography and mechanical properties of single molecules of type I collagen using atomic force microscopy

, 2005
Although the mechanical behavior of tendon and bone has been studied for decades, there is still relatively little understanding of the molecular basis for their specific properties.
Bozec, L., Laurent Bozec, Horton, Michael, Horton, M., Michael Horton, Bozec, Laurent   +5 more
core   +1 more source

Inhibition of Type I Collagen Expression in Fibrosis Prevention after Trabeculectomy: Oryctolagus cuniculus [PDF]

Nurwasis The administration of postoperative bevacizumab injection in subconjunctival trabeculectomy will reduce bleb fibrosis. This study aimed to investigate the effect of bevacizumab as an antifibrotic agent on collagen density, collagen thickness ...
Evelyn Komaratih, Evelyn, Heryawati, -, Nurwasis, -, Shinta Arta Wiguna, -   +3 more
core   +1 more source

Clinical significance and biological role of cancer‐derived Type I collagen in lung and esophageal cancers [PDF]

, 2019
Background Extracellular matrix (ECM) is remodeled during carcinogenesis. An abundant constituent of ECM is collagen. Type I collagen is secreted by fibroblasts, is important for tumor growth and epithelial‐mesenchymal transition, and may also be ...
Guan, X, Yongdong Dai, Mingming Yang, Li, J, Hu, L, Jiangchao Li, Dai, Y, Mei, Y, Shuo Fang, Xininyuan Guan, Yang, M, Yan Mei, Liang Hu, Fang, S, Yang, H, Hong Yang   +15 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Synthesis of type I collagen.

, 2014
(A) Western blots of cell lysates with antibodies to collagen 3-hydroxylation complex components. Lysates are derived from two independent cultures for each genotype. (B) SDS-Urea PAGE analysis of steady-state labeled type I collagen from wild-type (+/+),
Kenneth B. Tomer (589458), Sergey Leikin (80043), Irina Perdivara (589451), Kenneth M. Kozloff (589459), Wayne A. Cabral (589450), Elena N. Makareeva (589456), Joan C. Marini (323048), Angela R. Blissett (589453), Weizhong Chang (589454), Joseph E. Perosky (589455), Edward L. Mertz (589457), Mitsuo Yamauchi (589460), Masahiko Terajima (589452), MaryAnn Weis (167898), David R. Eyre (249083)   +14 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Heterogeneous nanomechanical properties of type I collagen in longitudinal direction

, 2017
Collagen is an abundant structural biopolymer in mammal vertebrates, providing structural support as well as mechanical integrity for connective tissues such as bone, ligament, and tendon.
Li, Tong, Burrage, Kevin, Tang, Ming, Gu, YuanTong, Gandhi, Neha S.   +4 more
core   +1 more source