An Escherichia coli effector protein promotes host mutation via depletion of DNA mismatch repair proteins. [PDF]
Enteropathogenic Escherichia coli (EPEC) is an attaching and effacing (A/E) human pathogen that causes diarrhea during acute infection, and it can also sustain asymptomatic colonization. A/E E.
Donnenberg, Michael S. +2 more
core +1 more source
Dihydromyricetin Regulates PANoptosis to Protect Salmonella Typhimurium‐Infected Weaned Piglets
After DHM pretreatment, piglets were subjected to Salmonella infection. Serum and ileocecal samples from the piglets were collected for TUNEL assay, Western blotting analysis, and metabolomics analysis. The results collectively indicated that DHM could protect piglets from Salmonella infection.
Tingting Xiao +6 more
wiley +1 more source
Small-Molecule Inhibitors of the Type III Secretion System
Drug-resistant pathogens have presented increasing challenges to the discovery and development of new antibacterial agents. The type III secretion system (T3SS), existing in bacterial chromosomes or plasmids, is one of the most complicated protein ...
Lingling Gu +4 more
doaj +1 more source
Tracking elusive cargo: Illuminating spatio-temporal type 3 effector protein dynamics using reporters [PDF]
Type 3 secretion systems (T3SS) form an integral part of the arsenal of many pathogenic bacteria. These injection machines, together with their cargo of subversive effector proteins are capable of manipulating the cellular environment of the host in ...
Connolly, James P.R. +2 more
core +1 more source
ABSTRACT Essential oils (EOs) exhibit antimicrobial activity against foodborne pathogens due to their chemical composition. This review investigates the mechanisms of action of EOs at subinhibitory concentrations against Salmonella strains. Even at subinhibitory concentrations, EOs induce cellular stress and modulate bacterial metabolism. EOs interfere
Carolina Ramos +5 more
wiley +1 more source
Fitting Pieces into the Puzzle of Pseudomonas aeruginosa Type III Secretion System Gene Expression
Type III secretion systems (T3SS) are widely distributed in Gram-negative microorganisms and critical for host-pathogen and host-symbiont interactions with plants and animals.
Emily A Williams McMackin +3 more
semanticscholar +1 more source
Enterobacter Species: Opportunistic Human and Plant Pathogens With Plant‐Beneficial Traits
The pathogen profile on Enterobacter species synthesises current knowledge on host range, disease symptoms, plant‐beneficial traits and compares genomic features within the genus. ABSTRACT Enterobacter species occur across diverse habitats and are best known for causing opportunistic and nosocomial infections in humans.
Sara Jordan +3 more
wiley +1 more source
Mechanistic Insights for Microbiome Application in Plant Disease Resistance
This review summarises the mechanisms underlying plant‐guided microbiome modulation and probiotic‐mediated disease suppression. Additionally, it highlights the challenges to be addressed for a better microbiome application of disease resistance in sustainable agriculture and proposes possible strategies. Figure was created with BioRender.
Jiakang Yin
wiley +1 more source
HilE regulates HilD by blocking DNA binding in Salmonella enterica serovar Typhimurium [PDF]
The Salmonella type three secretion system (T3SS), encoded in the Salmonella pathogenicity island 1 (SPI1) locus, mediates the invasion of the host intestinal epithelium.
Cott Chubiz, Jessica E +3 more
core +2 more sources
Ustilago hordei Delivers Heterologous Fungal Effectors for Screening and Characterisation in Wheat
Ustilago hordei, a barley pathogen, has been engineered to deliver effectors of fungal pathogens in wheat. Necrosis‐inducing activities of Parastagonospora nodorum effectors SnTOX1 and SnTOX3 can effectively be screened for. Challenges occur when stem rust fungus avirulence effectors are tested in this secretion system.
Lu Liu, Sang Hu Kim, Guus Bakkeren
wiley +1 more source

