Results 1 to 10 of about 17,578 (215)

Unraveling and Characterization of Novel T3SS Effectors in Edwardsiella piscicida.

MSphere, 2023
Type III secretion system (T3SS) facilitates survival and replication of Edwardsiella piscicida in vivo. Identifying novel T3SS effectors and elucidating their functions are critical in understanding the pathogenesis of E. piscicida. E.
He Tian, Hai Xia Xie, Pin Nie
exaly   +5 more sources

The Pseudomonas aeruginosa T3SS Can Contribute to Traversal of an in Situ Epithelial Multilayer Independently of the T3SS Needle.

MBio
Multilayered epithelia lining our tissue surfaces normally resist traversal by opportunistic bacteria. Previously, we developed a strategy to experimentally perturb this resistance in situ in the corneas of mouse eyes and used it to show that traversal ...
Suzanne Fleiszig, Arne Rietsch, David J Evans   +2 more
exaly   +6 more sources

Injectisome assembly primes Pseudomonas aeruginosa for type III secretion [PDF]

mBio
Many Gram-negative pathogens, including Pseudomonas aeruginosa, use a type III secretion system (T3SS) to intoxicate eukaryotic cells. The T3SS is an important virulence factor linked to increased morbidity and mortality in infections, yet its expression
Kristen Ramsey, Shoichi Tachiyama, Apolline Brossard, Zhao Hang, Jun Liu, Barbara I. Kazmierczak   +5 more
doaj   +2 more sources

PA5201 represses type III secretion system by binding to the PexsC promoter in Pseudomonas aeruginosa [PDF]

Microbiology Spectrum
The type III secretion system (T3SS) is a major virulence determinant in Pseudomonas aeruginosa, which is activated by the master regulator ExsA. exsA is transcribed from two distinct promoters: its operon promoter PexsC and its own promoter PexsA. Here,
Lepeng Wang, Chenyu Shen, Liwen Yin, Yu Zhang, Linyan Zhang, Shujun Liu, Zhihui Cheng, Weihui Wu, Un-Hwan Ha, Shouguang Jin, Yongxin Jin   +10 more
doaj   +2 more sources

Characterization of Virulence Function of Avirulence Protein E1 (AvrE1) during Host Plant Infection [PDF]

The Plant Pathology Journal, 2021
Pseudomonas cichorii secretes effectors that suppress defense mechanisms in host plants. However, the function of these effectors, including avirulence protein E1 (AvrE1), in the pathogenicity of P. cichorii, remains unexplored.
Duyen Do Tran Huong, Nagendran Rajalingam, Yong Hoon Lee   +2 more
doaj   +1 more source

Quorum Sensing Employs a Dual Regulatory Mechanism to Repress T3SS Gene Expression.

MBio
The type III secretion system (T3SS) is a needle-like complex used by numerous bacterial pathogens in host infection to inject exotoxins into the host cell cytoplasm. The T3SS is a known virulence factor in the shrimp pathogen Vibrio campbellii.
Logan J Geyman, Payel Paul, Douglas B Rusch   +2 more
exaly   +3 more sources

Bcr4 Is a Chaperone for the Inner Rod Protein in the Bordetella Type III Secretion System

Microbiology Spectrum, 2022
Bordetella bronchiseptica injects virulence proteins called effectors into host cells via a type III secretion system (T3SS) conserved among many Gram-negative bacteria.
Masataka Goto, Akio Abe, Tomoko Hanawa, Masato Suzuki, Asaomi Kuwae   +4 more
doaj   +1 more source

Genome Sequences of Two Pseudomonas aeruginosa Isolates with Defects in Type III Secretion System Gene Expression from a Chronic Ankle Wound Infection

Microbiology Spectrum, 2021
Effector proteins translocated into host cells by the Pseudomonas aeruginosa type III secretion system (T3SS) are critical for phagocytic avoidance and systemic spread of the microorganism. The T3SS genes are present in virtually all P.
Sardar Karash, Robert Nordell, Egon A. Ozer, Timothy L. Yahr   +3 more
doaj   +1 more source

INTERACTION OF SALMONELLA WITH HOST ORGANISM

Журнал микробиологии, эпидемиологии и иммунобиологии, 2017
Diseases caused by Salmonella enterica species bacteria remain a healthcare challenge. Salmonella enterica species is divided into typhoid serovars that cause systemic infection and non-typhoid serovars that most frequently have a course of ...
M. N. Boichenko, V. V. Zverev, E. V. Volchkova   +2 more
doaj   +1 more source

Mechanisms of bacillary dysentery: lessons learnt from infant rabbits

Gut Microbes, 2020
The bacterial pathogen Shigella flexneri causes more than 250 million cases of bacillary dysentery (blood in stool) every year across the world. This human-specific disease is characterized by profuse bloody diarrhea, dramatic ulceration of the colonic ...
Lauren K. Yum, Hervé Agaisse
doaj   +1 more source