Results 31 to 40 of about 17,578 (215)

Spermidine Is an Intercellular Signal Modulating T3SS Expression in Pseudomonas aeruginosa

Microbiology Spectrum, 2022
Type III secretion system (T3SS) is one of the pivotal virulence factors of Pseudomonas aeruginosa responsible for evading phagocytosis, and secreting and translocating effectors into host cells. Previous studies underline the complicated and elaborate regulatory mechanisms of T3SS for the accurate, fast, and ...
Qiqi Lin, Huishan Wang, Jiahui Huang, Zhiqing Liu, Qunyi Chen, Guohui Yu, Zeling Xu, Ping Cheng, Zhibin Liang, Lian-Hui Zhang   +9 more
openaire   +3 more sources

Injectisome T3SS Subunits As Potential Chaperones In The Extracellular Export of Pectobacterium Carotovorum Subsp. Carotovorum Bacteriocins Carocin S1 And Carocin S3 Secreted Via Flagellar T3SS [PDF]

BMC Microbiology, 2021
Abstract Pectobacterium carotovorum subsp. carotovorum (Pcc) causes soft-rot disease in a wide variety of plants resulting in economic losses worldwide. It produces various types of bacteriocin to compete against related plant pathogens. Studies on how bacteriocins are extracellularly secreted are conducted to understand the mechanism of ...
Huang-Pin Wu, Reymund C. Derilo, Han-Ling Chen, Tzu-Rung Li, Ruchi Briam James Lagitnay, Yin‐Ching Chan, Yutin Chuang, Duen‐Yau Chuang   +7 more
openaire   +4 more sources

Identification of specific sequence motif of YopN of Yersinia pseudotuberculosis required for systemic infection

Virulence, 2019
Type III secretion systems (T3SSs) are tightly regulated key virulence mechanisms shared by many Gram-negative pathogens. YopN, one of the substrates, is also crucial in regulation of expression, secretion and activation of the T3SS of pathogenic ...
Sarp Bamyaci, Roland Nordfelth, Åke Forsberg   +2 more
doaj   +1 more source

Identification of VPA1327 (vopT) as a Novel Genetic Marker for Detecting Pathogenic Vibrio parahaemolyticus

Journal of Pure and Applied Microbiology, 2018
Vibrio parahaemolyticus is a Gram-negative bacterium that is ubiquitous in marine and estuarine environments. The pathogenic strains can cause foodborne gastroenteritis especially when raw or undercooked seafood contaminated with pathogenic V ...
Phatcharaporn Chiawwit, Monchanok Boonyahong, Unchana Thawornwan, Potjanee Srimanote, Pongsri Tongtawe   +4 more
doaj   +1 more source

An Experimental Pipeline for Initial Characterization of Bacterial Type III Secretion System Inhibitor Mode of Action Using Enteropathogenic Yersinia

Frontiers in Cellular and Infection Microbiology, 2018
Dozens of Gram negative pathogens use one or more type III secretion systems (T3SS) to disarm host defenses or occupy a beneficial niche during infection of a host organism. While the T3SS represents an attractive drug target and dozens of compounds with
Jessica M. Morgan, Hanh N. Lam, Jocelyn Delgado, Justin Luu, Sina Mohammadi, Ralph R. Isberg, Helen Wang, Victoria Auerbuch   +7 more
doaj   +1 more source

LITESEC-T3SS-Light-controlled protein delivery into eukaryotic cells with high spatial and temporal resolution

, 2020
Many bacteria employ a type III secretion system (T3SS) injectisome to translocate proteins into eukaryotic host cells. Although the T3SS can efficiently export heterologous cargo proteins, a lack of target cell specificity currently limits its ...
Langenfeld, K., Milne-Davies, B., Lindner, F., Stiewe, T., Diepold, A.   +4 more
core   +1 more source

Piericidin A1 Blocks Yersinia Ysc Type III Secretion System Needle Assembly

mSphere, 2017
The type III secretion system (T3SS) is a bacterial virulence factor expressed by dozens of Gram-negative pathogens but largely absent from commensals.
Jessica M. Morgan, Miles C. Duncan, Kevin S. Johnson, Andreas Diepold, Hanh Lam, Allison J. Dupzyk, Lexi R. Martin, Weng Ruh Wong, Judith P. Armitage, Roger G. Linington, Victoria Auerbuch   +10 more
doaj   +1 more source

Phylogenetic analysis of a gene cluster encoding an additional, rhizobial-like type III secretion system that is narrowly distributed among Pseudomonas syringae strains

BMC Microbiology, 2012
Background The central role of Type III secretion systems (T3SS) in bacteria-plant interactions is well established, yet unexpected findings are being uncovered through bacterial genome sequencing.
Gazi Anastasia D, Sarris Panagiotis F, Fadouloglou Vasiliki E, Charova Spyridoula N, Mathioudakis Nikolaos, Panopoulos Nicholas J, Kokkinidis Michael   +6 more
doaj   +1 more source

Dynamic relocalization of cytosolic type III secretion system components prevents premature protein secretion at low external pH

Nature Communications, 2021
Many bacterial pathogens use a type III secretion system (T3SS) to inject effector proteins into host cells. Here, Wimmi et al. show that the external pH regulates the assembly of T3SS cytosolic components in intestinal pathogens, thus preventing T3SS ...
Stephan Wimmi, Alexander Balinovic, Hannah Jeckel, Lisa Selinger, Dimitrios Lampaki, Emma Eisemann, Ina Meuskens, Dirk Linke, Knut Drescher, Ulrike Endesfelder, Andreas Diepold   +10 more
doaj   +1 more source

Oleanolic acid induces the type III secretion system of Ralstonia solanacearum

Frontiers in Microbiology, 2015
Ralstonia solanacearum, the causal agent of bacterial wilt, can naturally infect a wide range of host plants. The type III secretion system (T3SS) is a major virulence determinant in this bacterium.
Dousheng eWu, Wei eDing, Yong eZhang, Xuejiao eLiu, Liang eYang   +4 more
doaj   +1 more source