Results 21 to 30 of about 17,578 (215)

Autoinducer-2 and bile salts induce c-di-GMP synthesis to repress the T3SS via a T3SS chaperone

Nature Communications, 2022
Abstract Cyclic di-GMP (c-di-GMP) transduces extracellular stimuli into intracellular responses, coordinating a plethora of important biological processes. Low levels of c-di-GMP are often associated with highly virulent behavior that depends on the type III secretion system (T3SS) effectors encoded, whereas ...
Shuyu Li, Hengxi Sun, Jianghan Li, Yujiao Zhao, Ruiying Wang, Lei Xu, Chongyi Duan, Jialin Li, Zhuo Wang, Qinmeng Liu, Yao Wang, Songying Ouyang, Xihui Shen, Lei Zhang   +13 more
openaire   +3 more sources

SPI2 T3SS effectors facilitate enterocyte apical to basolateral transmigration of Salmonella-containing vacuoles in vivo [PDF]

, 2021
Salmonella pathogenicity island (SPI) 2 type three secretion system (T3SS)-mediated effector molecules facilitate bacterial survival in phagocytes but their role in the intestinal epithelium in vivo remains ill-defined.
Pägelow, Dennis, Plendl, Johanna, Vorst, Kira van, Welitschanski, Katharina, Busche, Tobias, Fulde, Marcus, Westermann, Alexander J., Tedin, Karsten, Zhang, Kaiyi, Huei, Yong Chiun   +9 more
core   +2 more sources

Assembly and structure of the T3SS

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2014
The Type III Secretion System (T3SS) is a multi-mega Dalton apparatus assembled from more than twenty components and is found in many species of animal and plant bacterial pathogens. The T3SS creates a contiguous channel through the bacterial and host membranes, allowing injection of specialized bacterial effector proteins directly to the host cell. In
Burkinshaw, Brianne J., Strynadka, Natalie C.J.   +1 more
openaire   +2 more sources

Mechanism of intracellular bacterial parasitism

Журнал микробиологии, эпидемиологии и иммунобиологии, 2019
Algorithm of intracellular bacterial parasitism does not depend on if bacterium is obligate or facultative intracellular parasite. Depending on replicative niche’s localization intracellular bacterial parasites are divided onto cellular and vacuolated ...
M. N. Boichenko, E. O. Kravtsova, V. V. Zverev   +2 more
doaj   +1 more source

SlyA Regulates Type III Secretion System (T3SS) Genes in Parallel with the T3SS Master Regulator HrpL in Dickeya dadantii 3937 [PDF]

Applied and Environmental Microbiology, 2012
ABSTRACT The hypersensitive response and pathogenicity ( hrp ) genes of Dickeya dadantii 3937 encode a type III secretion system (T3SS) which is essential for its full virulence. Previous studies of the T3SS regulation in D.
Lifang, Zou, Quan, Zeng, Haiping, Lin, Prasad, Gyaneshwar, Gongyou, Chen, Ching-Hong, Yang   +5 more
openaire   +2 more sources

Expression of the Type III Secretion System Genes in Epiphytic Erwinia amylovora Cells on Apple Stigmas Benefits Endophytic Infection at the Hypanthium

Molecular Plant-Microbe Interactions, 2021
Erwinia amylovora causes fire blight on rosaceous plants. One of the major entry points of E. amylovora into hosts is flowers, where E. amylovora proliferates epiphytically on stigmatic and hypanthium surfaces and, subsequently, causes endophytic ...
Zhouqi Cui, Regan B. Huntley, Neil P Schultes, Kaleem U. Kakar, Ching-Hong Yang, Quan Zeng   +5 more
doaj   +1 more source

Novel Insight of Transcription Factor PtrA on Pathogenicity and Carbapenems Resistance in Pseudomonas aeruginosa

Infection and Drug Resistance, 2022
Ying Zhang,1,* Lingbo Wang,1,* Liqiong Chen,2 Peiwu Zhu,1 Na Huang,1 Tao Chen,1 Lijiang Chen,1 Zhongyong Wang,1 Wenli Liao,1 Jianming Cao,2 Tieli Zhou1 1Department of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical ...
Zhang Y, Wang L, Chen L, Zhu P, Huang N, Chen T, Chen L, Wang Z, Liao W, Cao J, Zhou T   +10 more
doaj  

Maintenance of tRNA and elongation factors supports T3SS proteins translational elongations in pathogenic bacteria during nutrient starvation

Cell & Bioscience, 2022
Background Sufficient nutrition contributes to rapid translational elongation and protein synthesis in eukaryotic cells and prokaryotic bacteria. Fast synthesis and accumulation of type III secretion system (T3SS) proteins conduce to the invasion of ...
Yue Sun, Xiaolong Shao, Yingchao Zhang, Liangliang Han, Jiadai Huang, Yingpeng Xie, Jingui Liu, Xin Deng   +7 more
doaj   +1 more source

Robustness and the evolution of length control strategies in the T3SS and flagellar hook

Biophysical Journal, 2021
Bacterial cells construct many structures, such as the flagellar hook and the type III secretion system (T3SS) injectisome, that aid in crucial physiological processes such as locomotion and pathogenesis. Both of these structures involve long extracellular channels, and the length of these channels must be highly regulated in order for these structures
Maulik K. Nariya, Abhishek Mallela, Jack J. Shi, Eric J. Deeds   +3 more
openaire   +4 more sources

ExsE Is a Negative Regulator for T3SS Gene Expression in Vibrio alginolyticus [PDF]

Frontiers in Cellular and Infection Microbiology, 2016
Type III secretion systems (T3SSs) contribute to microbial pathogenesis of Vibrio species, but the regulatory mechanisms are complex. We determined if the classic ExsACDE protein-protein regulatory model from Pseudomonas aeruginosa applies to Vibrio alginolyticus. Deletion mutants in V.
Jinxin Liu, Jinxin Liu, Shao-Yeh Lu, Lisa H. Orfe, Chun-Hua Ren, Chao-Qun Hu, Douglas Ruben Call, Johannetsy J. Avillan, Zhe Zhao, Zhe Zhao   +9 more
openaire   +3 more sources