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Comparison of <i>Galleria mellonella</i>, epithelial cell cytotoxicity, and mouse model of bacteremia to measure <i>Pseudomonas aeruginosa</i> virulence. [PDF]
Valdes A +24 more
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Secretion systems shaping host-pathogen interactions in Burkholderia species. [PDF]
Pallen S +8 more
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Structural basis of eukaryotic cell targeting by type III secretion system (T3SS) effectors
Research in Microbiology, 2013Type III secretion systems (T3SS) are macromolecular complexes that translocate a wide number of effector proteins into eukaryotic host cells. Once within the cytoplasm, many T3SS effectors mimic the structure and/or function of eukaryotic proteins in order to manipulate signaling cascades, and thus play pivotal roles in colonization, invasion ...
Andréa Dessen +2 more
exaly +4 more sources
Current Microbiology, 2023
Pseudomonas aeruginosa infection in seriously ill patients is a major concern due to its ability to form biofilm and secrete effector toxins. There is little information on the prevalence of T3SS effector toxins and biofilm production in clinical isolates of P. aeruginosa from Nigeria. The goal of this study is to evaluate the prevalence of T3SS toxins
Oluwatoyin B. Olaniran +3 more
openaire +2 more sources
Pseudomonas aeruginosa infection in seriously ill patients is a major concern due to its ability to form biofilm and secrete effector toxins. There is little information on the prevalence of T3SS effector toxins and biofilm production in clinical isolates of P. aeruginosa from Nigeria. The goal of this study is to evaluate the prevalence of T3SS toxins
Oluwatoyin B. Olaniran +3 more
openaire +2 more sources
Journal of Molecular Biology, 2011
Pseudomonas aeruginosa is an opportunistic human pathogen that employs a finely tuned type III secretion system (T3SS) to inject toxins directly into the cytoplasm of target cells. ExsB is a 15.6-kDa protein encoded in a T3SS transcription regulation operon that displays high sequence similarity to YscW, a lipoprotein from Yersinia spp.
Izoré, Thierry +5 more
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Pseudomonas aeruginosa is an opportunistic human pathogen that employs a finely tuned type III secretion system (T3SS) to inject toxins directly into the cytoplasm of target cells. ExsB is a 15.6-kDa protein encoded in a T3SS transcription regulation operon that displays high sequence similarity to YscW, a lipoprotein from Yersinia spp.
Izoré, Thierry +5 more
openaire +2 more sources
Microbial Pathogenesis, 2022
Gamma-proteobacteria is a class of gram-negative opportunistic pathogens existing in the intestinal flora, often leading to diarrhea and intestinal infectious diseases, and plays an important role in maintaining intestinal homeostasis. Type III secretion system (T3SS), an important virulence system, is closely related to the adhesion and invasion and ...
Ze-Yuan Gao +5 more
openaire +2 more sources
Gamma-proteobacteria is a class of gram-negative opportunistic pathogens existing in the intestinal flora, often leading to diarrhea and intestinal infectious diseases, and plays an important role in maintaining intestinal homeostasis. Type III secretion system (T3SS), an important virulence system, is closely related to the adhesion and invasion and ...
Ze-Yuan Gao +5 more
openaire +2 more sources

