An Interaction between the Inner Rod Protein YscI and the Needle Protein YscF Is Required to Assemble the Needle Structure of the Yersinia Type Three Secretion System. [PDF]
Cao SY +9 more
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Small Molecule Inhibitor of Type Three Secretion System Belonging to a Class 2,4-disubstituted-4H-[1,3,4]-thiadiazine-5-ones Improves Survival and Decreases Bacterial Loads in an Airway Pseudomonas aeruginosa Infection in Mice. [PDF]
Sheremet AB +7 more
europepmc +1 more source
Immune Response in Calves Vaccinated with Type Three Secretion System Antigens and Shiga Toxin 2B Subunit of Escherichia coli O157:H7. [PDF]
Martorelli L +8 more
europepmc +1 more source
Structure of the Core of the Type Three Secretion System Export Apparatus
Lucas Kuhlen +12 more
openalex +1 more source
Cross-talk between type three secretion system and metabolism in Yersinia
Neumayer, W. +6 more
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Targeting the Type Three Secretion System in Pseudomonas aeruginosa
Trends in Pharmacological Sciences, 2016The injectisome type three secretion system (T3SS) is a major virulence factor in Pseudomonas aeruginosa. This bacterium is responsible for severe infections in immunosuppressed or cystic fibrosis patients and has become resistant to many antibiotics. Inhibitors of T3SS may therefore constitute an innovative therapeutic target.
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Type three secretion system in Salmonella Typhimurium: the key to infection
Genes & Genomics, 2020Type Three Secretion Systems (T3SS) are nanomachine complexes, which display the ability to inject effector proteins directly into host cells. This skill allows for gram-negative bacteria to modulate several host cell responses, such as cytoskeleton rearrangement, signal transduction, and cytokine production, which in turn increase the pathogenicity of
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