Characterization of the Mesorhizobium loti MAFF303099 Type-Three Protein Secretion System [PDF]
Molecular Plant-Microbe Interactions, 2009 Type III secretion systems (T3SS) have been found in several species of rhizobia. Proteins (termed effectors) secreted by this system are involved in host-range determination and influence nodulation efficiency.
Cintia Sánchez +4 more
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Structural and Functional Characterization of the Type Three Secretion System (T3SS) Needle of Pseudomonas aeruginosa [PDF]
Frontiers in Microbiology, 2019 The type three secretion system (T3SS) is a macromolecular protein nano-syringe used by different bacterial pathogens to inject effectors into host cells. The extracellular part of the syringe is a needle-like filament formed by the polymerization of a 9-
Charlotte Lombardi +17 more
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The type three secretion system effector protein IpgB1 promotes Shigella flexneri cell-to-cell spread through double-membrane vacuole escape. [PDF]
PLoS Pathogens, 2022 S. flexneri is an important human pathogen that causes bacillary dysentery. During infection, S. flexneri invades colonic epithelial cells, hijacks the host cell cytoskeleton to move in the cytosol of infected cells, and spreads from cell to cell through
Erin A Weddle +3 more
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PLoS Pathogens, 2014 Delivery of microbial products into the mammalian cell cytosol by bacterial secretion systems is a strong stimulus for triggering pro-inflammatory host responses. Here we show that Salmonella enterica serovar Typhi (S.
Sebastian E Winter +12 more
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Salmonella Pathogenicity Island 1 (SPI-1): The Evolution and Stabilization of a Core Genomic Type Three Secretion System [PDF]
Microorganisms, 2020 Salmonella Pathogenicity Island 1 (SPI-1) encodes a type three secretion system (T3SS), effector proteins, and associated transcription factors that together enable invasion of epithelial cells in animal intestines. The horizontal acquisition of SPI-1 by
Nicole A. Lerminiaux +2 more
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Terazosin Interferes with Quorum Sensing and Type Three Secretion System and Diminishes the Bacterial Espionage to Mitigate the <i>Salmonella</i> Typhimurium Pathogenesis. [PDF]
Antibiotics (Basel), 2022 Hegazy WAH +4 more
europepmc +3 more sources
Transmembrane substrates of type three secretion system injectisomes. [PDF]
Microbiology (Reading), 2023 The type three secretion system injectisome of Gram-negative bacterial pathogens injects virulence proteins, called effectors, into host cells. Effectors of mammalian pathogens carry out a range of functions enabling bacterial invasion, replication, immune suppression and transmission.
Godlee C, Holden DW.
europepmc +4 more sources
An insertion sequence-dependent plasmid rearrangement in Aeromonas salmonicida causes the loss of the type three secretion system. [PDF]
PLoS ONE, 2012 Aeromonas salmonicida, a bacterial fish pathogen, possesses a functional Type Three Secretion System (TTSS), which is essential for its virulence. The genes for this system are mainly located in a single region of the large pAsa5 plasmid.
Katherine H Tanaka +4 more
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Plasmid composition in Aeromonas salmonicida subsp. salmonicida 01-B526 unravels unsuspected type three secretion system loss patterns [PDF]
BMC Genomics, 2017 Background Aeromonas salmonicida subsp. salmonicida is a ubiquitous psychrophilic waterborne bacterium and a fish pathogen. The numerous mobile elements, especially insertion sequences (IS), in its genome promote rearrangements that impact its phenotype.
Katherine H. Tanaka +5 more
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Dynamic interaction of the Yersinia pseudotuberculosis type three secretion system proteins LcrV and LcrG. [PDF]
Protein SciMangu JCK +9 more
europepmc +3 more sources