Results 61 to 70 of about 604,658 (175)
mBio, 2021 CpnT, a NAD + glycohydrolase, is the only known toxin that is secreted by Mycobacterium tuberculosis . CpnT is composed of two domains; the C-terminal domain is the toxin, whereas the N-terminal domain is required for secretion.
B. Izquierdo Lafuente +4 more
openaire +6 more sources
Kinetic Characterization of the Shigella Type Three Secretion System ATPase Spa47 Using α-32P ATP
Bio-Protocol, 2018 ATPases represent a diverse class of enzymes that utilize ATP hydrolysis to support critical biological functions such as driving ion pumps, providing mechanical work, unfolding/folding proteins, and supporting otherwise thermodynamically unfavorable ...
Heather Case, Nicholas Dickenson
doaj +1 more source
mBio, 2023 The type VIIb secretion system (T7SSb) is a multisubunit protein export machine found in Gram-positive Bacillota which plays a key role in interbacterial competition.
Yaping Yang +5 more
doaj +1 more source
Bacterial control of pores induced by the Type Three Secretion System: Mind the gap
Frontiers in Immunology, 2016 Type Three secretion Systems (T3SSs) are specialized secretion apparatus involved in the virulence of many Gram-negative pathogens, enabling the injection of bacterial type III effectors into host cells. The T3SS-dependent injection of effectors requires
Julie eGuignot +7 more
doaj +1 more source
Frontiers in Microbiology, 2019 Virulent Aeromonas hydrophila causes severe motile Aeromonas septicemia in warmwater fishes. In recent years, channel catfish farming in the U.S.A. and carp farming in China have been affected by virulent A.
Hasan C. Tekedar +5 more
doaj +1 more source
Analysis of effectors of the Salmonella Typhimurium SPI‐2 type three secretion system
, 2011 Salmonella enterica serovar Typhimurium (S. Typhimurium), an intracellular pathogen, causes gastroenteritis in humans and a systemic disease in mice. The ability of Salmonella to replicate inside host cells requires translocation of effector proteins across the vacuolar membrane, mediated by the Salmonella pathogenicity island‐2 (SPI‐2) type three ...
Ana Rita Figueira
openalex +4 more sources
Gut Microbes, 2021 Many pathogens use M cells to access the underlying Peyer’s patches and spread to systemic sites via the lymph as demonstrated by ligated loop murine intestinal models.
Alyssa C. Fasciano +7 more
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Frontiers in Microbiology, 2019 The GacS/GacA two-component system is essential for virulence in many plant pathogenic bacteria, and thus represents a promising anti-virulence target.
Bo Zhang +4 more
doaj +1 more source
Diversity of virulence phenotypes among type III secretion negative Pseudomonas aeruginosa clinical isolates. [PDF]
PLoS ONE, 2014 Pseudomonas aeruginosa is a frequent cause of acute infections. The primary virulence factor that has been linked to clinical disease is the type III secretion system, a molecular syringe that delivers effector proteins directly into host cells.
Jonida Toska +6 more
doaj +1 more source