Results 71 to 80 of about 7,552,757 (287)

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

Advanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab, Jack F. Murphy, Michael Bartolf‐Kopp, Jenny C‐C Hsin, Alice Chernaik, Frank McCaughan, Yan Yan Shery Huang, Tomasz Jungst, Jürgen Groll   +8 more
wiley   +1 more source

Epidermolysis bullosa pruriginosa: A report of two cases

Indian Dermatology Online Journal, 2014
Epidermolysis bullosa (EB) pruriginosa is a very rare pattern of dystrophic EB caused by type VII collagen gene mutation, with distinctive clinico-pathological features. It is characterized by nodular prurigo-like lichenified lesions, nail dystrophy, and
Varadraj Vasant Pai, Tukaram Sori, Kikkeri Narayanshetty Naveen, Sharatchandra Bhimrao Athanikar, Vijetha Rai, Dinesh Udupi Shastry   +5 more
doaj   +1 more source

Functional Correction of Type VII Collagen Expression in Dystrophic Epidermolysis Bullosa [PDF]

Journal of Investigative Dermatology, 2011
Functional defects in type VII collagen, caused by premature termination codons on both alleles of the COL7A1 gene, are responsible for the severe autosomal recessive types of the skin blistering disease, recessive dystrophic epidermolysis bullosa (RDEB).
Murauer, Eva M., Gache, Yannick, Gratz, Iris K., Klausegger, Alfred, Muss, Wolfgang, Gruber, Christina, Meneguzzi, Guerrino, Hintner, Helmut, Bauer, Johann W.   +8 more
openaire   +2 more sources

Hierarchical nanomechanics of collagen microfibrils [PDF]

, 2010
Collagen constitutes one third of the human proteome, providing mechanical stability, elasticity and strength to connective tissues. Collagen is also the dominating material in the extracellular matrix (ECM) and is thus crucial for cell differentiation ...
Alberto Redaelli, Markus J. Buehler, Alfonso Gautieri, Simone Vesentini   +3 more
core  

Bioengineered Interfaces for Peripheral Nerve Sensory Restoration

Advanced Materials, EarlyView.
Half of amputees abandon their prosthetics for lack of feeling. This review charts the full path from peripheral nerve injury to restored sensation, through surgical, regenerative, noninvasive, and implanted approaches, and shows how injury type and interface material properties determine which strategy can deliver naturalistic feedback, and why ...
Sydney Swedick, Salim El Hadwe, Kesi Liang, George G. Malliaras, Damiano G. Barone   +4 more
wiley   +1 more source

Mutation Analyses of COL7A1 Gene in Three Taiwanese Patients with Severe Recessive Dystrophic Epidermolysis Bullosa

Journal of the Formosan Medical Association, 2007
Dystrophic epidermolysis bullosa (DEB) is a hereditary mechanobullous disorder characterized by fragility of the skin and mucous membranes caused by abnormal anchoring fibrils.
Sheau-Chiou Chao, Julia Yu-Yun Lee
doaj   +1 more source

IgE does not increase collagen type-IV deposition, but increases collagen type-VII diseases specifically.

, 2013
(A) IgE does not induce collagen type-IV deposition by ASMC. (B) IgE does not modify TGF-β1-induced collagen type-IV deposition. (C) IgE disease specifically increases the deposition of collagen type-VII by ASMC of asthma patients, (D) but has no ...
Michael Tamm (65010), Chong Teck S’ng (283750), Jun Zhong (236780), Stephanie Goulet (283752), Michael Roth (283746), Celine Zumkeller (283749)   +5 more
core   +1 more source

Surface Functionalization Modulates Collective Cell Behavior Near Topological Defects Induced by Topographical Patterning

Advanced Materials Interfaces, EarlyView.
Strongly adhered cells align with concentric circular ridges and exhibit predominantly tangential motion, whereas weakly adhered cells fail to follow topographical guidance and display enhanced radial inward motion. ABSTRACT Living cells establish long‐range orientational order through collective alignment, giving rise to topological defects whose ...
Prasoon Awasthi, Aniruddh Murali, Ellen Juel Pørtner, Adam Cohen Simonsen, Francesca Serra   +4 more
wiley   +1 more source

Bacteriodes fragilis interactions with the collagen type I component of the host extracellular matrix [PDF]

, 2010
Includes bibliographical references (p. 116-126).Bacteroides fragilis is an opportunistic pathogen which can cause life threatening infections in humans and animals.
Galvao, Bruna Patricia Gomes de Vasconcelos
core   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source