The Missense Mutation p.R1303Q in Type XVII Collagen Underlies Junctional Epidermolysis Bullosa Resembling Kindler Syndrome [PDF]
Cristina Has +12 more
openalex +1 more source
Bullous pemphigoid is an inflammatory subepidermal blistering skin disease associated with an IgG autoimmune response to the type XVII collagen. The immunopathologic features of bullous pemphigoid can be reproduced in mice by the passive transfer of anti-type XVII collagen antibodies.
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Pathogenic relevance of autoantibodies to type XVII collagen from pemphigoid gestationis patients [PDF]
Pemphigoid gestationis (PG) and bullous pemphigoid (BP) are subepidermal autoimmune blistering diseases characterized by self-reactive T and B cells specific for the transmembrane hemidesmosomal protein type XVII collagen/BP180. Major T and B cell epitopes are located within the immunodominant 16th non-collagenous domain A (NC16A) of type XVII collagen.
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Type XVII collagen coordinates proliferation in the interfollicular epidermis
Type XVII collagen (COL17) is a transmembrane protein located at the epidermal basement membrane zone. COL17 deficiency results in premature hair aging phenotypes and in junctional epidermolysis bullosa. Here, we show that COL17 plays a central role in regulating interfollicular epidermis (IFE) proliferation.
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012 Treg dysfunction induces autoantibodies to type XVII collagen and BP230 in mice and humans [PDF]
Ken Muramatsu +6 more
openalex +1 more source
Oral lichen planus with low-titer autoantibodies to BP180 and desmoglein 3
Miki Sato +5 more
doaj +1 more source
Autoimmunity to Collagen XVII (BP180-Ag2) in Pemphigoid Associated With Parkinson's Disease. [PDF]
Cid-Puente R +5 more
europepmc +1 more source
Type XVII collagen is a deterministic factor of epidermal patterning
配架番号:2597 (主査) 教授 畠山 鎮次, 准教授 舟山 恵美, 教授 近藤 亨 医学院(医学専攻)
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Novel frameshift variant in exon 7 of COL17A1 in a domestic shorthair kitten with junctional epidermolysis bullosa. [PDF]
Fussell D +6 more
europepmc +1 more source

