Results 91 to 100 of about 1,963,903 (303)

Copyright and Digitization and Preservation of State Government Documents: A Detailed Analysis

open access: yesJournal of Copyright in Education and Librarianship, 2016
This paper builds off "Copyright and the Digitization of State Government Documents: A Preliminary Analysis" presented at IPres 2015. In this paper, we present a more detailed analysis and a practical framework for local archivists and librarians to use
Brett D. Currier   +2 more
doaj   +1 more source

Ensemble clustering for result diversification [PDF]

open access: yes, 2012
This paper describes the participation of the University of Twente in the Web track of TREC 2012. Our baseline approach uses the Mirex toolkit, an open source tool that sequantially scans all the documents.
Hiemstra, Djoerd, Nguyen, Dong-Phuong
core   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Manuscriptorium Digital Library and ENRICH Project: Means for Dealing with Digital Codicology and Palaeography [PDF]

open access: yes, 2009
Codicology and palaeography in the digital age can be developed both through adapting existing methods and using information and communication technologies.
Knoll, Adolf, Uhlíř, Zdeněk
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Patterns and Types for Querying XML Documents [PDF]

open access: yes, 2005
In order to manipulate XML data, a programming or query language should provide some primitives to deconstruct them, in particular to pinpoint and capture some subparts of the data. Among various proposals for primitives for deconstructing XML data, two different and complementary approaches seem to clearly stem from practise: path expressions ...
openaire   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Documenting API Input/Output Examples

open access: yes, 2017
When learning to use an Application Programming Interface (API), programmers need to understand the inputs and outputs (I/O) of the API functions. Current documentation tools automatically document the static information of I/O, such as parameter types ...
Armaly, Ameer   +4 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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