Results 91 to 100 of about 168,919,123 (296)

An Unifying Replacement Approach for Caching Systems

open access: yesJournal of Communications Software and Systems, 2007
A cache replacement algorithm called probability based replacement (PBR) is proposed in this paper. The algorithm makes replacement decision based on the byte accessprobabilities of documents.
Kai-Hau Yeung   +2 more
doaj  

De stem van de ervaring: egodocumenten in historisch onderzoek naar drugsgebruik

open access: yesLocus
Throughout history, drug users have recorded their personal experiences with drugs and the meanings that their use had for them in words and images. These personal sources or ‘ego documents’ give outsiders access to the user's perspective. However, their
Eefje Körner
doaj   +1 more source

Visual Types of Greek Documents from Late Antique Egypt

open access: yes, 2018
This paper presents a general overview of some of the visual features of Greek documents that originate from Egypt’s multilingual environment in the period from the fourth to the eighth centuries CE.
Tost, Sven (University of Vienna)
core  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Library Historical Documents (S2_B27_F1_14)

open access: yes, 2020
Historical documents inside a glass case in the University of Akron ...
University of Akron
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Library Historical Documents (S2_B27_F1_4)

open access: yes, 2020
Historical documents inside a glass case in the University of Akron ...
University of Akron
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

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