Results 71 to 80 of about 1,963,903 (303)

How is equity approached in universal health coverage? An analysis of global and country policy documents in Benin and Senegal

open access: yesInternational Journal for Equity in Health, 2019
Background Equity seems inherent to the pursuance of universal health coverage (UHC), but it is not a natural consequence of it. We explore how the multidimensional concept of equity has been approached in key global UHC policy documents, as well as in ...
Elisabeth Paul   +7 more
doaj   +1 more source

TGSum: Build Tweet Guided Multi-Document Summarization Dataset [PDF]

open access: yes, 2015
The development of summarization research has been significantly hampered by the costly acquisition of reference summaries. This paper proposes an effective way to automatically collect large scales of news-related multi-document summaries with reference
Cao, Ziqiang   +5 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Classifying document types to enhance search and recommendations in digital libraries

open access: yes, 2017
In this paper, we address the problem of classifying documents available from the global network of (open access) repositories according to their type. We show that the metadata provided by repositories enabling us to distinguish research papers, thesis ...
F Sebastiani   +2 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Guidance from key organisations on exploring, confirming and interpreting subgroup effects of medical treatments: a scoping review

open access: yesBMJ Open, 2019
Objectives With the increasing interest in personalised medicine, the use of subgroup analyses is likely to increase. Subgroup analyses are challenging and often misused, possibly leading to false interpretations of the effect. It remains unclear to what
Johannes B Reitsma   +7 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An Unifying Replacement Approach for Caching Systems

open access: yesJournal of Communications Software and Systems, 2007
A cache replacement algorithm called probability based replacement (PBR) is proposed in this paper. The algorithm makes replacement decision based on the byte accessprobabilities of documents.
Kai-Hau Yeung   +2 more
doaj  

Evaluation of an Internet Document Delivery Service [PDF]

open access: yes, 2001
An Internet-based Document Delivery Service (DDS) has been developed within the framework of the CNR ( the Italian Research National Council) Project BiblioMIME, in order to take advantage of new Internet technologies and promote cooperation among ...
Abba, Laura   +4 more
core  

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