Results 11 to 20 of about 3,977 (192)

The Burden of Typhoid and Paratyphoid in India: Systematic Review and Meta-analysis

PLoS Neglected Tropical Diseases, 2016
BackgroundTyphoid is an important public health challenge for India, especially with the spread of antimicrobial resistance. The decision about whether to introduce a public vaccination programme needs to be based on an understanding of disease burden ...
Jacob John, Nicholas C Grassly
exaly   +6 more sources

WHO preferred product characteristics for bivalent Salmonella Typhi/Paratyphi A vaccine for comprehensive protection against enteric fever– key considerations and research gaps [version 1; peer review: awaiting peer review] [PDF]

Gates Open Research
In 2021, Salmonella Paratyphi A caused >2 million illnesses, resulting in >14,000 deaths, most of which occurred among children under 5 years of age in socioeconomically deprived populations.
Denise O. Garrett, John A. Crump, Jacob John, Melita A. Gordon, Matthew B. Laurens, Karen H. Keddy, Florian Marks, Xinxue Liu, Senjuti Saha, Andrew J. Pollard, Annelies Wilder-Smith, Ana Belen Ibarz Pavon, Alejandro Craviotto, John Clemens   +13 more
doaj   +5 more sources

Complex Adaptive Immunity to enteric fevers in humans: Lessons learned and the path forward [PDF]

Frontiers in Immunology, 2014
Salmonella enterica serovar Typhi (S. Typhi), the causative agent of typhoid fever, and S. Paratyphi A and B, causative agents of paratyphoid fever, are major public health threats throughout the world.
Marcelo B. Sztein, Rosangela eSalerno-Goncalves, Monica A Mcarthur   +2 more
doaj   +8 more sources

Phase II multicentre double-blind randomised controlled trial of a Bivalent VaccInation against Salmonella Typhi and Paratyphi A (BiVISTA) using a controlled human infection model of paratyphoid A infection: study protocol [PDF]

BMJ Open
Introduction Enteric fever, primarily caused by Salmonella enterica Typhi and Salmonella enterica Paratyphi A (SPA), is endemic mainly in South Asia, disproportionately affecting school-age children.
Elizabeth Jones, Xinxue Liu, Andrew J Pollard, Brian Angus, Parvinder Aley, Eleanor Wilson, Hannah Robinson, Amy Flaxman, Prasad S Kulkarni, Nisha Singh, Naina McCann, Young Chan Kim, Margarete Paganotti Vicentine, Oisin Hennigan, Noshi Maria, Claudia I Juarez Molina, Stanislava Koleva, Mohammod K Islam, Nicole Day, Allison MacDonald, Mehreen Adnan, Sophie Vernon, Anirudha Vyankatesh Potey, Abhijeet Dharmadhikari, Sanket Gaidhane, Maheshi Nirmala Ramasamy   +25 more
doaj   +2 more sources

Shifting Enteric Fever Epidemiology in children in Nepal: Is the Burden of Paratyphi on the Rise? [PDF]

Journal of Nepal Medical Association
Nepal has a high burden of enteric fevers. An observational study conducted in a tertiary-level hospital in Nepal over 11 years (2014–2024), reviewing hospital records of all blood culture-positive cases of Salmonella Typhi and Paratyphi in children ...
Shrijana Shrestha, Sanjeev Man Bijukchhe, Saugat Bhandari, Meeru Gurung   +3 more
doaj   +2 more sources

Preclinical evaluation of multivalent vaccine combinations against Shigella and Salmonella infections [PDF]

Frontiers in Immunology
Shigellosis is an intestinal infection causing severe and often life-threatening diarrheal disease, with high prevalence in children under five years of age in low- and middle-income countries.
Roberta Di Benedetto, Roberta Di Benedetto, Rebecca Nappini, Salvatore Gemmellaro, Federica Boretto, Valentina Caradonna, Martina Carducci, Paola Cescutti, Omar Rossi, Francesca Mancini, Francesco Berlanda Scorza, Simona Rondini, Carlo Giannelli, Renzo Alfini, Francesca Micoli   +14 more
doaj   +2 more sources

Review of current typhoid fever vaccines, cross-protection against paratyphoid fever, and the European guidelines

Expert Review of Vaccines, 2017
Introduction: Typhoid and paratyphoid fever remain a global health problem, which – in non-endemic countries – are mainly seen in travelers, particularly in VFRs (visiting friends and relatives), with occasional local outbreaks occurring.
Jane N Zuckerman, Christoph Hatz, Anu Kantele   +2 more
exaly   +2 more sources

Development and characterization of high-throughput serological assays to measure magnitude and functional immune response against S. Paratyphi A in human samples [PDF]

Frontiers in Immunology
Typhoid and Paratyphoid fever cause a global health burden, especially for the children of Southern Asia. The impact of the disease is further exacerbated by the dramatic increase of antimicrobial resistance.
Martina Carducci, Luisa Massai, Elisa Lari, Bianca Semplici, Silvia Grappi, Noshi Maria, Elizabeth Jones, Valentino Conti, Pietro Piu, Francesco Berlanda Scorza, Miren Iturriza-Gómara, Emanuele Montomoli, Emanuele Montomoli, Andrew J. Pollard, Simona Rondini, Omar Rossi   +15 more
doaj   +2 more sources

The Salmonella Paratyphi A O-Antigen Glycoconjugate Vaccine Is Able to Induce Antibodies with Bactericidal Activity Against a Panel of Clinical Isolates [PDF]

Vaccines
Background: Typhoid and paratyphoid fevers represent a global health burden, especially in Southern Asia, exacerbated by the increase in antimicrobial resistance.
Marika Pinto, Salvatore Durante, Martina Carducci, Luisa Massai, Renzo Alfini, Elli Mylona, Abhilasha Karkey, Stephen Baker, Francesca Micoli, Carlo Giannelli, Omar Rossi, Simona Rondini   +11 more
doaj   +2 more sources

TYPHOID-PARATYPHOID VACCINATION WITH MIXED VACCINES [PDF]

BMJ: British Medical Journal, 1913
Aldo Castellani
exaly   +3 more sources