Results 1 to 10 of about 16,673 (201)

Impact of the COVID-19 pandemic and typhoid conjugate vaccine introduction on typhoid fever in Nepal. [PDF]

PLoS Neglected Tropical Diseases
BackgroundWhile typhoid conjugate vaccines (TCV) offer promise for reducing risk in endemic settings, their population-level impact remains unclear.
Dipesh Tamrakar, Shiva Ram Naga, Esther Jung, Basudha Shrestha, Pratibha Bista Roka, Rabin Pokharel, Sabin Bikram Shahi, Aarjya Tara Bajracharya, Surendra K Mahadup, Nishan Katuwal, Kate Doyle, Jessica C Seidman, Alice S Carter, Stephen P Luby, Isaac I Bogoch, Kristen Aiemjoy, Denise O Garrett, Rajeev Shrestha, Jason R Andrews   +18 more
doaj   +3 more sources

Introduction of typhoid vaccine in the expanded immunization program of Pakistan [PDF]

Human Vaccines & Immunotherapeutics, 2021
Worldwide, typhoid infects 11–20 million people each year. In Pakistan, the first extensively drug-resistant (XDR) typhoid was reported in 2016 resulting in an epidemic.
Fahmida Aslam, Yang Yue, Majid Aziz
doaj   +2 more sources

A multicenter, single-blind, randomized, phase-2/3 study to evaluate immunogenicity and safety of a single intramuscular dose of biological E’s Vi-capsular polysaccharide-CRM197 conjugate typhoid vaccine (TyphiBEVTM) in healthy infants, children, and adults in comparison with a licensed comparator [PDF]

Human Vaccines & Immunotherapeutics, 2022
The current scenario of typhoid fever warrants early prevention with typhoid conjugate vaccines in susceptible populations to provide lifelong protection.
Subhash Thuluva, Vikram Paradkar, Ramesh Matur, Kishore Turaga, Subba Reddy GV   +4 more
doaj   +2 more sources

Phase II multicentre double-blind randomised controlled trial of a Bivalent VaccInation against Salmonella Typhi and Paratyphi A (BiVISTA) using a controlled human infection model of paratyphoid A infection: study protocol [PDF]

BMJ Open
Introduction Enteric fever, primarily caused by Salmonella enterica Typhi and Salmonella enterica Paratyphi A (SPA), is endemic mainly in South Asia, disproportionately affecting school-age children.
Elizabeth Jones, Xinxue Liu, Andrew J Pollard, Brian Angus, Parvinder Aley, Eleanor Wilson, Hannah Robinson, Amy Flaxman, Prasad S Kulkarni, Nisha Singh, Naina McCann, Young Chan Kim, Margarete Paganotti Vicentine, Oisin Hennigan, Noshi Maria, Claudia I Juarez Molina, Stanislava Koleva, Mohammod K Islam, Nicole Day, Allison MacDonald, Mehreen Adnan, Sophie Vernon, Anirudha Vyankatesh Potey, Abhijeet Dharmadhikari, Sanket Gaidhane, Maheshi Nirmala Ramasamy   +25 more
doaj   +2 more sources

Burden of typhoid fever and antimicrobial resistance in India (2023): a modelling studyResearch in context [PDF]

The Lancet Regional Health - Southeast Asia
Summary: Background: India is one of the countries with a high typhoid fever burden. In 2022, the National Technical Advisory Group on Immunisation recommended including the typhoid conjugate vaccine (TCV) in the Universal Immunisation Programme.
Vijayalaxmi V. Mogasale, Jacob John, Nikhil Sahai, Arindam Ray, Habib Hasan Farooqui, Vittal Mogasale, Bhim Gopal Dhoubhadel, W. John Edmunds, Andrew Clark, Kaja Abbas   +9 more
doaj   +2 more sources

Effective strategies for typhoid conjugate vaccine delivery: Health and economic insights from the 2015 Kampala outbreak. [PDF]

PLoS Neglected Tropical Diseases
Typhoid fever remains a major public health threat in low- and middle-income countries (LMICs), where inadequate access to clean water and sanitation drives recurrent outbreaks.
Yeonsu Lee, Pamela Kim N Salonga, Changdae Son, Geunsoo Jang, Dae-Hyup Koh, Jong-Hoon Kim, Hyojung Lee   +6 more
doaj   +2 more sources

Prevention of Typhoid Fever by Existing Improvements in Household Water, Sanitation, and Hygiene, and the Use of the Vi Polysaccharide Typhoid Vaccine in Poor Urban Slums: Results from a Cluster-Randomized Trial. [PDF]

Am J Trop Med Hyg, 2022
Im J, Khanam F, Ahmmed F, Kim DR, Kang S, Tadesse BT, Chowdhury F, Ahmed T, Aziz AB, Hoque M, Islam MT, Park J, Liu X, Sur D, Pak G, Jeon HJ, Zaman K, Khan AI, Qadri F, Marks F, Kim JH, Clemens JD.   +21 more
europepmc   +3 more sources

Comparative Epidemiology of Salmonella enterica Serovers Paratyphi A and Typhi Causing Enteric Fever, Bangladesh, 2018–2020 [PDF]

Emerging Infectious Diseases
Enteric fever remains a public health challenge. We analyzed data from a cluster-randomized Vi-tetanus toxoid conjugate vaccine trial to compare the epidemiology between Salmonella enterica serovars Paratyphi A, which causes paratyphoid fever, and Typhi,
Sadia Isfat Ara Rahman, Md Golam Firoj, Se Eun Park, Farhana Khanam, Suneth Agampodi, Kassa Haile, Edilawit Mesfin, Faisal Ahmmed, Md Taufiqul Islam, Ashraful Islam Khan, Fahima Chowdhury, Afroza Akter, Martin Bundi Mwebia, Justin Im, Natasha Y. Rickett, Cecilia Kathure Mbae, Asma Binte Aziz, Beatrice Ongadi, Moses Mwangi, Benjamin Ngugi, Meseret Gebre Behute, Kelvin Kering, Suman Kanungo, Xinxue Liu, Deok Ryun Kim, Andrew J. Pollard, K Zaman, Samuel Kariuki, Firdausi Qadri, John D. Clemens   +29 more
doaj   +2 more sources

Modeling the initial impact and predicted future benefits of TCV from two Pakistani provincesResearch in context [PDF]

The Lancet Regional Health - Southeast Asia
Summary: Background: While trials have demonstrated high efficacy of typhoid conjugate vaccine (TCV), data on effectiveness are limited. We report initial impacts and predict future benefits of TCV from two provinces in Pakistan.
Alicia N.M. Kraay, Mohammad T. Yousafzai, Sonia Qureshi, Jillian Gauld, Farah N. Qamar   +4 more
doaj   +2 more sources

Restoring non-COVID-19 clinical research and surveillance in Oyo state, Nigeria during the SARS-CoV-2 pandemic

Journal of Public Health in Africa, 2022
Background: Many sub-Saharan African patients receive clinical care from extramurally-supported research and surveillance. During the COVID-19 pandemic, pausing these activities reduces patient care, surveillance, and research staff employment ...
Veronica O. Ogunleye, Okainemen P. Oluwalusi, Oluwafemi Popoola, Aderemi Kehinde, Olukemi Adekanmbi, Ifiok Udofia, Sarah Agbi, Ifeoluwa Akintayo, Jolaade J. Ajiboye, Folasade Bamidele, Temitope Alonge, Ondari D. Mogeni, Florian Marks, Iruka N. Okeke   +13 more
doaj   +1 more source