3',5'-Cyclic Adenosine Monophosphate- and Ca2+-Calmodulin-Dependent Endogenous Protein Phosphorylation Activity in Membranes of the Bovine Chromaffin Secretory Vesicles: Identification of Two Phosphorylated Components as Tyrosine Hydroxylase and Protein Kinase Regulatory Subunit Type II [PDF]
, 1983 : Membranes of the secretory vesicles from bovine adrenal medulla were investigated for the presence of the endogenous protein phosphorylation activity. Seven phosphoprotein bands in the molecular weight range of 250,000 to 30,000 were observed by means ...
Weber, W., Treiman, M., Gratzl, Manfred
core +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Hydroxyl Radical Induced Ultra-Weak Photon Emission from Tyrosine Solutions
, 2015 This paper deals with ultra-weak photon emission (UPE) from aqueous tyrosine solutions induced by hydroxyl radical. The physical nature of this specific phenomenon is presented and the proposed mechanism of its origin during oxidation of tyrosine is ...
Michal Cifra +4 more
core +1 more source
, 2021 A method of creating nanoclusters (NCs) from soluble peptide molecules is described utilizing an approach based on a tyrosine-tyrosine cross-linking reaction.
Gaurav Joshi +7 more
core +1 more source
Transcriptomic insights into the effects of tyrosine on sub-Columbian plumage in H line chickens
Frontiers in Veterinary ScienceTyrosine is known to influence melanin generation; however, its involvement in melanin production in chicken feathers is unknown. We evaluated the feather color of H-line chickens fed diets containing different concentrations of tyrosine (0, 0.4, 0.6, 0 ...
Xinlei Wang +17 more
doaj +1 more source
Novel Strecker degradation products of tyrosine and dihydroxyphenylalanine
Czech Journal of Food Sciences, 2001 Tyrosine was oxidised with either potassium peroxodisulphate or glyoxal. Volatile reaction products were isolated and analysed by GC/FID and GC/MS, derivatised with diazomethane and analysed by the same methods.
J. Adamiec +3 more
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
pharmacological application of tyrosine kinase inhibitors in certain malinancies
, 2019 The use of targeted therapy to inhibit tyrosine kinases, as a form of cancer chemotherapy is one of the major medical advances in the past decade. Tyrosine kinases activate many signal transduction cascades by adding a phosphate group to proteins and ...
Peslin, Pavel
core
ErbB2 signaling in breast cancer : the role of ErbB, Akt and ShcA phosphorylation [PDF]
, 2004 Breast cancer is the most common malignancy in women and is estimated to account for more than 200,000 new cancer cases in the United States in the year 2002. It now represents the second leading cause of death (40,000) from cancer in women.
Cicenas, Jonas
core +1 more source
Veterinary SciencesThe objective of this study was to evaluate the effect of tyrosine on behavior and ruminal meta-taxonomic profile of Altay sheep. Twelve rams with the lowest behavioral responses to humans and twelve rams with the highest behavioral responses were sorted
Asmita Thapa +6 more
doaj +1 more source