Results 81 to 90 of about 880,315 (306)
Large scale structural analysis of protein tyrosine phosphatases
, 2009 Protein tyrosine phosphatases (PTPs) are essential regulators of signal transduction pathways, and control, together with protein tyrosine kinases (PTKs), the reversible phosphorylation of tyrosine residues. PTPs are, from a structural biology viewpoint,
Barr, A.J., Knapp, S.
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Siliao yanjiu, 2022 The experiment was to study the effect of dietary tyrosine supplementation on slaughter performance and meat quality of Yufen 1 H line chickens. Eighty 21-week-old Yufen 1 H line chickens were randomly divided into five groups, with four replicates in ...
Xin-lei WANG +7 more
doaj
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Structure and Dynamic Properties of Solid l-Tyrosine-Ethylester as Seen by 13C MAS NMR
, 2016 13C MAS NMR experiments on solid l-tyrosine-ethylester with 13C in low natural abundance and in fully 13C enriched form are reported. The phenyl rings are found to undergo π flips with a rather low activation energy Ea = 50 ± 12 kJ mol-1.
Angelika Sebald (2688904) +1 more
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Molecular networks in FGF signaling: Flotillin-1 and Cbl-associated protein compete for the binding to fibroblast growth factor receptor substrate 2 [PDF]
, 2012 Fibroblast growth factor receptor substrate 2 (FRS2α) is a signaling adaptor protein that regulates downstream signaling of many receptor tyrosine kinases.
Traub Stephanie +11 more
core +2 more sources
Indian Journal of OphthalmologyPurpose: To observe the spectroscopic profile of human lens in different age groups and varying grades of cataract and to use the data to arrive at differentiating molecular biology. Design: An observational cross-sectional study.
Ayasha Nishad, Praveen Malik, Taru Dewan
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Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
International Journal of Electrochemical Science, 2018 In this paper, a novel electrochemical sensor based on molecularly imprinted polypyrrole film at gold electrode for selective and sensitive detection of tyrosine (Tyr) was fabricated.
Nihal Ermiş, Nihat Tınkılıç
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source