Results 251 to 260 of about 1,534,933 (399)

Modulus‐Switchable Miniature Robots for Biomedical Applications: A Review

Advanced Robotics Research, EarlyView.
Materials, robot designs, proof‐of‐concept functions, and biomedical applications of modulus‐switchable miniature robots. Miniature soft robots have shown great potential in biomedical applications due to their excellent controllability and suitable mechanical properties in biological environments.
Chunyun Wei, Yibin Wang, Jiangfan Yu
wiley   +1 more source

Molecular Mechanisms and Treatment Strategies of ALK-Positive Lung Cancer: A Beginner's Guide for Patients, Their Families and Carers. [PDF]

Thorac Cancer
Klenova E.
europepmc   +1 more source

Paraformaldehyde fixation and some characteristics of lens proteins as measured by Raman microspectroscopy [PDF]

, 1990
Greve, J., Huizinga, Alex, Mul, Frits F.M. de, Schyns, Mario W.R.J., Vrensen, Gijs F.J.M.   +4 more
core   +2 more sources

NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22.

Journal of Clinical Investigation, 2016
M. Spalinger, S. Kasper, C. Gottier, S. Lang, K. Atrott, S. Vavricka, S. Scharl, T. Raselli, I. Frey-Wagner, Petrus G. M. Gutte, M. Grütter, H. Beer, E. Contassot, A. Chan, X. Dai, D. Rawlings, F. Mair, B. Becher, W. Falk, M. Fried, G. Rogler, M. Scharl   +21 more
semanticscholar   +1 more source

Engineering of an Ancestral McbA with Enhanced Domain Mobility Extends Biocatalytic Amide Synthesis Scope

Advanced Synthesis &Catalysis, EarlyView.
We show how engineered ancestral amide bond synthetases (ABSs) together with cofactor recycling using a single polyphosphate kinase paves the way for chemoenzymatic synthesis of pharmacophores. The figure illustrates how ancestral ABS has a more flexible C‐terminal domain, which is associated with enhanced catalytic performance and expanded amine scope.
Elisabeth Söderberg, Marianne R. Molenaar, Katarzyna Zaczyk, Magnus Johansson, Martin A. Hayes, Per‐Olof Syrén   +5 more
wiley   +1 more source

The Fer Tyrosine Kinase Mediates EGFR Activation in Sperm Capacitation. [PDF]

Int J Mol Sci
Yemini-Talbi O, Nir U, Breitbart H.
europepmc   +1 more source

CRISPR‐MI and scRNA‐Seq Reveal TREM2's Function in Monocyte Infiltration and Macrophage Apoptosis During Abdominal Aortic Aneurysm Development

Advanced Science, EarlyView.
A method is developed for conducting genome‐wide CRISPR/Cas9 screening of monocyte infiltration in vivo (CRISPR‐MI) that is easily adaptable across a variety of disease models. Through the combination of CRISPR‐MI and scRNA‐Seq, this study discovers that Trem2 is a key regulator of early monocyte infiltration in abdominal aortic aneurysm (AAA ...
Haocheng Lu, Chao Xue, Yang Zhao, Jinjian Sun, Changzhi Zhao, Xu Zhang, Guizhen Zhao, Yaozhong Liu, Hongyu Liu, Yongjie Deng, Ying Wang, Chi Zhang, Yingjie Liu, Linjun Zeng, Ying Yang, Bolun Li, Shusi Ding, Linkang Zhou, Henry Kuang, Zanxin Wang, Wenhao Ju, Haihuan Lin, Jie Lin, Yanhong Guo, Lin Chang, Hongmei Zhao, Jing Wang, Jiandie Lin, Lemin Zheng, Y. Eugene Chen, Jifeng Zhang   +30 more
wiley   +1 more source

The association between aromatic amino acids consumption and the severity of pemphigus vulgaris: a cross-sectional study. [PDF]

Sci Rep
Mostafazadeh P, Nouri A, Najafi A, Balighi K, Daneshpazhooh M, Ebrahimpour-Koujan S.   +5 more
europepmc   +1 more source

Nitric oxide, oxidants, and protein tyrosine nitration

Proceedings of the National Academy of Sciences of the United States of America, 2004
R. Radi
semanticscholar   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source