Results 81 to 90 of about 1,021,136 (197)

Multi tyrosine kinase inhibitor dasatinib as novel cause of severe pre-capillary pulmonary hypertension? [PDF]

, 2011
Jan K. Hennigs, Gunhild Keller, Hans Jörg Baumann, Friedemann Honecker, Stefan Kluge, Carsten Bokemeyer, Tim H. Brümmendorf, Hans Klose   +7 more
openalex   +1 more source

Genistein, a specific inhibitor of tyrosine-specific protein kinases.

Journal of Biological Chemistry, 1987
Tetsu AkiyamaSO, Junko IshidaST, Suguru NakagawaS, H. Ogawara, Shun‐ichi Watanabe, Noriki Itoh, Masabumi ShibuyaSS, Y. Fukami   +7 more
semanticscholar   +1 more source

Diabetic Kidney Disease: Contribution of Phenyl Sulfate Derived from Dietary Tyrosine upon Gut Microbiota Catabolism

Biomolecules
Deranged gut microbiota can release increased levels of uremic toxins leading to exacerbated kidney injury. In diabetic kidney disease (DKD), phenyl sulfate (PS) derived from tyrosine catabolism by gut microbiota has been demonstrated to be both an early
Haoxin Liu, Tram N. Diep, Ying Wang, Yucheng Wang, Liang-Jun Yan   +4 more
doaj   +1 more source

The autism-associated MET receptor tyrosine kinase engages early neuronal growth mechanism and controls glutamatergic circuits development in the forebrain [PDF]

, 2016
Yun Peng, Zhengqi Lu, Guohui Li, Mariel Piechowicz, Miranda J. Anderson, Y Uddin, Jie Wu, Shenfeng Qiu   +7 more
openalex   +1 more source

Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome.

New England Journal of Medicine, 2001
B. Druker, C. Sawyers, H. Kantarjian, D. Resta, Sofia Fernandes Reese, J. Ford, R. Capdeville, M. Talpaz   +7 more
semanticscholar   +1 more source

FBXO3-mediated DUSP9 ubiquitination reprograms MAPK signaling to eradicate tyrosine kinase inhibitor-resistant CML stem cells [PDF]

Xudong Li, Shiyu Zuo, B. Zhang, Zhenghua Huang, Rongfeng Xu, Mengjia Li, Hong Huang, Yaomei Wang, Yongping Song, Baijun Fang, Bian Zhilei, Wei Li   +11 more
openalex   +1 more source

The Tyrosine Kinase Pyk2 Promotes Migration and Invasion of Glioma Cells

, 2005
Christopher A. Lipinski, Nhan L. Tran, Emmanuel Menashi, Carole Rohl, Jean Kloss, R. Curtis Bay, Michael E. Berens, Joseph C. Loftus   +7 more
openalex   +1 more source

Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity

, 2008
Stanley D. Chamberlain, Anikó M. Redman, Joseph W. Wilson, Felix Deanda, J. Brad Shotwell, Roseanne Gerding, Huangshu Lei, Bin Yang, Kirk L. Stevens, Anne M. Hassell, Lisa M. Shewchuk, M. Anthony Leesnitzer, Jeffery L. Smith, Peter Sabbatini, Charity Atkins, Arthur Groy, Jason L. Rowand, Rakesh Kumar, Robert A. Mook, Ganesh S. Moorthy, Samarjit Patnaik   +20 more
openalex   +1 more source

mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt.

Cancer Research, 2006
K. O'reilly, F. Rojo, Q. She, D. Solit, G. Mills, Debra L. Smith, H. Lane, F. Hofmann, D. Hicklin, D. Ludwig, J. Baselga, N. Rosen   +11 more
semanticscholar   +1 more source

Accumulation of membrane glycoproteins in lysosomes requires a tyrosine residue at a particular position in the cytoplasmic tail. [PDF]

, 1990
Mark A. Williams, Minoru Fukuda
openalex   +1 more source