Results 301 to 310 of about 1,906,742 (351)

Bruton’s tyrosine kinase (Btk)—the critical tyrosine kinase in LPS signalling?

Immunology Letters, 2004
The discovery of the Toll-like receptors (TLRs) has revolutionised the field of innate immunity. One unresolved question regarding LPS signalling is whether there is a role for tyrosine kinases downstream of the LPS receptor. Studies in mice deficient in Bruton's tyrosine kinase have previously shown that they are defective in their responses to LPS ...
Caroline A, Jefferies, Luke A J, O'Neill
openaire   +2 more sources

Tyrosine kinases in neutrophils

Current Opinion in Hematology, 1999
Nonreceptor tyrosine kinases have been shown to represent essential components of several signal transduction pathways implicated in neutrophil activation. Engagement of phagocytic, cytokine, chemoattractant, and adhesion receptors transduces intracellular signals via distinct tyrosine kinases.
openaire   +3 more sources

Nuclear protein tyrosine kinases

Trends in Biochemical Sciences, 1994
Protein tyrosine phosphorylation plays an important role in the transduction of extracellular signals. The prototypical protein tyrosine kinases are localized at the plasma membrane and are coupled to receptors that bind extracellular factors. Thus, protein tyrosine phosphorylation was previously thought to occur only in the cytoplasm. However, several
openaire   +2 more sources

Tyrosine protein kinase assays

Journal of Chromatography B: Biomedical Sciences and Applications, 1996
Protein kinases form a large family of enzymes that play a major role in a number of live processes. The study of their action is important for the understanding of the transformation mechanisms and of the normal and pathological growth events. The quality of an enzyme assay is often the key point of an enzymatic study.
openaire   +2 more sources

PROTEIN-TYROSINE KINASES

Annual Review of Biochemistry, 1985
T, Hunter, J A, Cooper
openaire   +2 more sources

IRS-1-Mediated Inhibition of Insulin Receptor Tyrosine Kinase Activity in TNF-α- and Obesity-Induced Insulin Resistance

Science, 1996
G. Hotamisligil, P. Peraldi, A. Budavari, Ramsey Ellis, M. White, B. Spiegelman   +5 more
semanticscholar   +1 more source

Tyrosine Kinases

2006
  +4 more sources

The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor.

Science, 1992
C. Vries, J. Escobedo, H. Ueno, K. Houck, N. Ferrara, L. Williams   +5 more
semanticscholar   +1 more source

Treatment of renal cell carcinoma: Current status and future directions

Ca-A Cancer Journal for Clinicians, 2017
Pedro Coelho Barata, Brian I Rini
exaly  

Lung cancer: New biological insights and recent therapeutic advances

Ca-A Cancer Journal for Clinicians, 2011
Suresh S Ramalingam, Fadlo R Khuri
exaly