Results 191 to 200 of about 313,710 (255)

Case Report: Secondary neurolymphomatosis successfully treated with sequential Bruton's tyrosine kinase inhibitor and bispecific antibody therapy. [PDF]

Front Oncol
Oura M, Toho M, Ikeda D, Fukuda N, Torres AS, Fujii F, Sakuma H, Uehara A, Tabata R, Narita K, Takeuchi M, Matsue K.   +11 more
europepmc   +1 more source

Aortic valve disease: Novel animal models for advancing our understanding of the underlying mechanisms

Animal Models and Experimental Medicine, EarlyView.
Due to the complex pathophysiology of aortic valve disease (AVD) and the resulting lack of effective pharmacotherapy, existing animal models are valuable research tools, but each has its own strengths and limitations. This review systematically surveys the major AVD models, compares their induction methods, pathological features, advantages and ...
Liya Hou, Xue Liu, Wangxing Hu, Xianbao Liu, Wei Zhu   +4 more
wiley   +1 more source

Association of Pre-Transplant Tyrosine Kinase Inhibitor Therapy With Tumor Response and Survival in Hepatocellular Carcinoma: A 10-Year Retrospective Cohort Study of 427 Patients. [PDF]

World J Surg
Xu L, Zhao Z, Wang Z, Zhao Z, Mu F, Zhou C, Ye Z, Zhang X, Wang Y, Lan T, Cao W, Zhang Y, Qi J, Hou Y, Shi J, Lu J, Tian M, Lv Y, Qu P, Hu L, Wang B.   +20 more
europepmc   +1 more source

Stabilizing Functional Nucleic Acids for Real‐Sample Diagnostics

Angewandte Chemie, EarlyView.
Functional nucleic acids enable programmable real‐sample diagnostics, but often lose function in complex biological matrices. This review highlights four stabilization levers—chemical, topological, architectural, and microenvironment/interface engineering—that preserve aptamer and DNAzyme performance in saliva, serum, urine, and stool, reframing ...
Soyeon Lee, Letizia Dondi, Amal Mathai, Connor Nurmi, Yingfu Li   +4 more
wiley   +1 more source

Oral mucositis risk with EGFR tyrosine kinase inhibitor monotherapies and combination regimens in non-small cell lung cancer: a systematic review and network meta-analysis. [PDF]

Front Immunol
Sun H, Yao Y, Liu X, Qiu R, Chen J, Zhang G, Shu Q.   +6 more
europepmc   +1 more source

Multi-target tyrosine kinase inhibitor-associated renal thrombotic microangiopathy: a pooled analysis of 31 cases. [PDF]

Front Pharmacol
Liu M, Zhou X.
europepmc   +1 more source

The <i>CD70</i>/<i>CD27</i> Axis in Tyrosine Kinase Inhibitor-Treated Chronic Phase Chronic Myeloid Leukemia Cells Is Not an Achilles Heel. [PDF]

Hematol Rep
Cassels J, Drotar ME, MacNeil A, Moles MW, Hsieh YC, Clarke CJ, Forde E, Jackson L, Elliott MA, Jacobs J, Zabrocki P, Copland M, Wheadon H, Michie AM, Jørgensen HG.   +14 more
europepmc   +1 more source

Actions of Midostaurin as Cation Channel and Tyrosine Kinase Inhibitor in Diffuse Intrinsic Pontine Glioma Cell Lines. [PDF]

Cancers (Basel)
Antonacci M, Di Turi A, Miciaccia M, Denora M, Maqoud F, Perrone MG, Scilimati A, Tricarico D.   +7 more
europepmc   +1 more source

Longitudinal analysis of tyrosine kinase inhibitor therapy outcomes and BCR-ABL1 transcript decline velocity in chronic myeloid leukemia: A 16-year real-world study. [PDF]

Cancer
Mustafa Ali MK, Zabor EC, Abdurakhmanov K, Zureigat H, Mohamed AN, Alchirazi MA, Dhakal A, Mushtaq A, Rehman N, Bawwab A, Berube B, Khatib L, Jain AG, Molina JC, Balderman S, Singh A, Gerds AT, Sobecks R, Advani AS, Carraway HE, Kalaycio M, Mukherjee S.   +21 more
europepmc   +1 more source

Hydroxyurea Bridging Before Frontline Tyrosine Kinase Inhibitor Therapy in Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia: A Critical Appraisal.

Oncology
Abdulgayoom M, Alshurafa A, Al-Mashdali AF, F Mohamed S, Yassin MA.   +4 more
europepmc   +1 more source