Results 251 to 260 of about 519,424 (350)

One-Year Ultralong Intravitreal Release of Tyrosine Kinase Inhibitor from Supramolecular Temperature-Responsive Hydrogel. [PDF]

Biomacromolecules
Zhao X, Lin Q, Seah I, Tan QSW, Goh RZR, Mehta KN, Liu Z, Tan A, How SEA, Sim B, Mota-Santiago P, Kirby N, Leow Y, Lim CC, Boo YJ, Goh SS, Lim JYC, Loh XJ, Su X.   +18 more
europepmc   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Analysis of long-term TNF-alpha induced EGFR tyrosine kinase inhibitor resistance in chordoma. [PDF]

RSC Med Chem
Tang H, Zhu Q, Fan J, Li X, Yan Z, Wang F, Wang H, Wang D.   +7 more
europepmc   +1 more source

Spatially Resolved Multiomics Reveals Metabolic Remodeling and Autophagy Activation in Adamantinomatous Craniopharyngiomas

Advanced Science, EarlyView.
Multiomics integration analysis reveals the “cystic fluid–tumor cell” metabolic coupling that mediates active choline/ethanolamine uptake of tumor cells from cystic fluid and PC/PE synthesis pathways reprogramming that mediating autophagy pathway activation within ACP. ABSTRACT Adamantinomatous craniopharyngioma (ACP), a benign yet highly recurrent and
Dongting Chen, Yahui Gao, Yulin Wang, Ting Lei, Zheng Qu, Yuhan An, Jiaxu Fu, Xin Li, Fangjun Liu, Yan Li   +9 more
wiley   +1 more source

MUCIN 1 confers inflammatory memory of tyrosine kinase inhibitor resistance in non-small cell lung cancer. [PDF]

Signal Transduct Target Ther
Takamori S, Haratake N, Bhattacharya A, Kikutake C, Ozawa H, Shigeta K, Nakashoji A, Isozaki H, Shimokawa M, Suyama M, Hashinokuchi A, Takada K, Toyokawa G, Yamada Y, Takenaka T, Taguchi K, Yamaguchi M, Yoshizumi T, Hata AN, Kufe D.   +19 more
europepmc   +1 more source

Sulfate‐Directed Silver Dendrites with Enhanced Stability for Ultrasensitive SERS‐Based Therapeutic Drug Monitoring

Advanced Science, EarlyView.
This study presents sulfate‐directed silver dendrites (s‐AgDs) as oxidation‐resistant SERS substrates with long‐term stability, reproducibility, and sub‐picomolar sensitivity. Sulfate ions guide anisotropic growth and protect the surface, enabling improved performance over 7 months under ambient conditions.
Aradhana Dwivedi, Jan Dellith, Anna Makarova, Samir F. El‐Mashtoly, Juergen Popp, Vladimir Sivakov, Dana Cialla‐May   +6 more
wiley   +1 more source

Acute myolysis in patients on tyrosine kinase inhibitor therapy for chronic myeloid leukemia. [PDF]

Am J Blood Res
Lipton JH.
europepmc   +1 more source