Results 211 to 220 of about 857,410 (384)

Porphyromonas gingivalis fimbria-stimulated bone resorption in vitro is inhibited by a tyrosine kinase inhibitor [PDF]

, 1995
Shigemasa Hanazawa, Yasuhiro Kawata, Yukio Murakami, K Naganuma, Shigeru Amano, Y Miyata, S Kitano   +6 more
openalex   +1 more source

COPS5 Triggers Ferroptosis Defense by Stabilizing MK2 in Hepatocellular Carcinoma

Advanced Science, EarlyView.
COPS5, which is overexpressed in HCC in an amplification‐ and ATF4‐dependent manner, stabilizes MK2 through deubiquitination and, in turn, induces HSPB1 activation, protecting HCC cells from ferroptosis and thus promoting sorafenib resistance and tumor progression. Abstract Sorafenib, which is proven to serve as a potent ferroptosis inducer, is used as
Ai‐Ling Luo, Wen‐Ying Zheng, Qiong Zhang, Yan Yuan, Mei‐Qi Li, Kai Du, An‐Ran Gao, Li‐Jun Pei, Jie Xie, Wen‐Hao Chen, Long Zhang, Xiu‐Zhu Guo, Xiao‐Ran Yang, Chao Zeng, Guo‐Hua Yang, Min Deng   +15 more
wiley   +1 more source

2. Tyrosine Kinase Inhibitors

Nihon Naika Gakkai Zasshi, 2007
openaire   +3 more sources

Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor

, 1998
David W. Fry, Alexander J. Bridges, William A. Denny, Annette M. Doherty, Kenneth D. Greis, James L. Hicks, Kenneth E. Hook, Paul R. Keller, Wilbur R. Leopold, Joseph A. Loo, Dennis J. McNamara, James M. Nelson, Veronika Sherwood, Jeff B. Smaill, Susanne Trumpp-Kallmeyer, Ellen M. Dobrusin   +15 more
openalex   +1 more source

A potent protein‐tyrosine kinase inhibitor which selectively blocks proliferation of epidermal growth factor receptor‐expressing tumor cells in vitro and in vivo. Int. J. Cancer, 76, 154–163 (1998) [PDF]

, 1999
N. Lydon, H. Mett, M. Mueller, M. Becker, R.M. Cozens, D. Daniels, P. Traxler, E. Buchdunger, D. Stover   +8 more
openalex   +1 more source

Cardiomyocyte‐Enriched USP20 Ameliorates Pathological Cardiac Hypertrophy by Targeting STAT3 Deubiquitination

Advanced Science, EarlyView.
Cardiomyocyte‐enriched USP20 regulates the K63‐linked ubiquitination of STAT3, and the cardiomyocyte‐specific USP20‐STAT3‐CARM1 axis exerts a protective role in cardiac hypertrophy. Targeting USP20 through cardiac‐specific gene therapy presents a promising strategy for the treatment of cardiac hypertrophy.
Lingfeng Zhong, Shanshan Dai, Fan Yu, Guo‐Ping Shi, Qinyan Gong, Yucong Zhang, Jingsi Duan, Zhengyin Lou, Zhixuan Tang, Fuzhe Gong, Derong Chen, Liya Hou, Xinyang Hu, Jinghai Chen, Jian'an Wang, Deling Yin   +15 more
wiley   +1 more source

Concomitant Genetic Alterations With Response to Treatment and Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Patients With EGFR-Mutant Advanced Non–Small Cell Lung Cancer

JAMA Oncology, 2018
Shaodong Hong, Fangfang Gao, Sha Fu, Yan Wang, W. Fang, Yan Huang, Li Zhang   +6 more
semanticscholar   +1 more source

Tyrosine kinase inhibitors in Ewing's sarcoma: a systematic review. [PDF]

BMC Cancer
Assi A, Farhat M, Mohanna R, Hachem MCR, Zalaquett Z, Aoun M, Farraj SA, Daher M, Sebaaly A, Kourie HR.   +9 more
europepmc   +1 more source

Semicochliodinol A and B: Inhibitors of HIV-1 Protease and EGF-R Protein Tyrosine Kinase Related to Asterriquinones Produced by the Fungus Chrysosporium merdarium.

, 1997
Andreas Fredenhagen, Frank Petersen, Marina Tintelnot‐Blomley, Johannes Rösel, Helmut Mett, Paul Hug   +5 more
openalex   +2 more sources

EFFECT OF INHIBITORS OF PROTEIN KINASE C(PKC) AND PROTEIN TYROSINE KINASE(PTK) ON THE CEREBROVASCULAR RESPONSE TO ADENOSINE 2276 [PDF]

, 1996
L Craig Wagerle, Sang Joo Kim, Pierantonio Russo   +2 more
openalex   +1 more source