Results 131 to 140 of about 5,768,655 (280)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
A U-Net Architecture for Inpainting Lightstage Normal Maps
ComputersIn this paper, we investigate the inpainting of normal maps that were captured from a lightstage. Occlusion of parts of the face during performance capture can be caused by the movement of, e.g., arms, hair, or props.
Hancheng Zuo, Bernard Tiddeman
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Deep learning-enabled generative acceleration for topology-optimized structures in 2D and 3D domain
Discover Artificial IntelligenceLatest research explored into how Deep Learning (DL) can be used to accelerate topology optimization while reducing processing costs. Topology optimization, relying on finite element analysis (FEA) and iterative solvers, typically incurs substantial ...
S Kanmani, M. Murali
doaj +1 more source
Geocarto InternationalForest Canopy Closure (CC) is vital for assessing forest ecosystems. This study integrates multispectral imagery with enhanced U-Net models (U-Net, U-Net++, U-Net3+) to achieve cost-effective large-scale CC estimation.
Lei Chen +5 more
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
2025 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops (CVPRW)Published in CVPR Workshops (CVMI), 2025. Project page/code/models/dataset: $\href{https://slavkoprytula.github.io/IAUNet/}{\text{this https URL}}$
Yaroslav Prytula +3 more
openaire +4 more sources
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source