Results 131 to 140 of about 295,660 (323)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

IAUNet: Instance-Aware U-Net

2025 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops (CVPRW)
Published in CVPR Workshops (CVMI), 2025. Project page/code/models/dataset: $\href{https://slavkoprytula.github.io/IAUNet/}{\text{this https URL}}$
Prytula, Yaroslav, Tsiporenko, Illia, Zeynalli, Ali, Fishman, Dmytro   +3 more
openaire   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

A Comparative Analysis of U-Net Architectures with Dimensionality Reduction for Agricultural Crop Classification Using Hyperspectral Data

Algorithms
The inherent high dimensionality of hyperspectral imagery presents both opportunities and challenges for agricultural crop classification. This study offers a rigorous comparative evaluation of three U-Net-based architectures, i.e., U-Net, U-Net++, and ...
Georgios Dimitrios Gkologkinas, Konstantinos Ntouros, Eftychios Protopapadakis, Ioannis Rallis   +3 more
doaj   +1 more source

Lunar surface image restoration using U-Net based deep neural networks

, 2020
Hiya Roy, Subhajit Chaudhury, Toshihiko Yamasaki, Danielle DeLatte, M. Ohtake, Tatsuaki Hashimoto   +5 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Enhancing medical image segmentation through stacked u-net architectures with interconnected convolution layers

Egyptian Informatics Journal
The effective integration of convolutional neural networks (CNNs), particularly as exemplified by the U-Net architecture, has led to notable advancements in medical image segmentation.
Abeer Aljohani
doaj   +1 more source

Optimized U-Net Segmentation and Hybrid Res-Net for Brain Tumor MRI Images Classification [PDF]

, 2021
R. Rajaragavi, S. Palanivel Rajan
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source