Results 121 to 130 of about 2,848,207 (306)
Advanced Optical Materials, EarlyView.Goos‐Hänchen shift (GHS) is a phenomenon in which an optical beam experiences a longitudinal displacement upon total internal reflection. In this work, we experimentally demonstrate an enhanced GHS in the wavelength domain using a helical fiber grating (HFG).
Zhang Meng +7 more
wiley +1 more source
WHY NOTCH GEOMETRY MATTERS FOR STRUCTURAL AND AUTOMOTIVE APPLICATIONS: A NUMERICAL SIMULATION
Rekayasa MesinIn structural and automotive systems, notches—whether from manufacturing defects or in-service damage—often act as critical stress concentrators that compromise component integrity.
Muhammad Akhsin Muflikhun +3 more
doaj +1 more source
Micromachined Double‐Membrane Mechanically Tunable Metamaterial for Thermal Infrared Filtering
Advanced Photonics Research, Volume 6, Issue 5, May 2025.Herein, a mechanically tunable double‐layer plasmonic metamaterial leveraging the extraordinary optical transmission effect observed in subwavelength arrays of openings within thin metal layers is presented. The concept is experimentally validated by integrating the proposed metamaterial structure into an electrostatic parallel‐plate actuator to create
Oleg Bannik +7 more
wiley +1 more source
Continuum Mechanics Modeling of Flexible Spring Joints in Surgical Robots
Advanced Robotics Research, EarlyView.A new mechanical model of a tendon‐actuated helical extension spring joint in surgical robots is built using Cosserat rod theory. The model can implicitly handle the unknown contacts between adjacent coils and numerically predict spring shapes from straight to significantly bent under actuation forces.
Botian Sun +3 more
wiley +1 more source
Hybrid Continuum Robot Designs and Architectures for Healthcare Applications
Advanced Robotics Research, EarlyView.Hybrid continuum robots represent an emerging class of flexible manipulators that blend materials, structures, and actuation concepts from the established fields of soft and continuum robotics. This review introduces an accessible framework to distinguish key hybridization approaches, surveys current designs aimed at complex clinical applications, and ...
Burak Ozdemir +4 more
wiley +1 more source
Cell and molecular biology of Notch.
Journal of Endocrinology, 2007 U. Fiuza, A. M. Arias
semanticscholar +1 more source
Advanced Science, EarlyView.This study reports that SBNO1 protein is upregulated in several cancer entities. SBNO1 protein interacts with the basal transcription factor TFIID via TAF4, enabling its recruitment to transcription start sites and the modulation of target gene expression.
Sarah Fritzsche +21 more
wiley +1 more source
Advanced Science, EarlyView.Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck +8 more
wiley +1 more source
Advanced Science, EarlyView.This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang +7 more
wiley +1 more source
Advanced Science, EarlyView.Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider +20 more
wiley +1 more source