Results 131 to 140 of about 44,552 (307)

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source

Wide range brittle fracture curves for U-notched components based on UMTS model

Engineering Solid Mechanics, 2013
Article history: Received January 20, 2013 Received in Revised form July, 2, 2013 Accepted 6 August 2013 Available online 7 August 2013 Extensive brittle fracture curves are presented in the present paper for engineering components weakened by a U-shaped notch under different in-plane loading conditions from pure mode I to pure mode II. The curves were
openaire   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Bioengineered 3D hPSC‐Cholangiocyte Ducts With Physiological Signals for Biliary Disease Modeling

Advanced Healthcare Materials, EarlyView.
Tian and colleagues generated a bioengineered bile duct from human pluripotent stem cell (hPSC)‐derived intrahepatic cholangiocytes within a high‐throughput, 384‐well platform to systematically examine the influence of biliary physiological signals including fluid flow, stromal cells and bile acids, and models intrahepatic biliary disease progression ...
Britney Tian, Mina Ogawa, Manami Kondo, Gabrielle Langeveld, Ling Jun Huan, Feng Zhang, Andrew Hollinger, Sara Deir, Christine Bear, Boyang Zhang, Shinichiro Ogawa   +10 more
wiley   +1 more source

Soft Neural Interfaces for Circuit‐Level Analysis of Magnetogenetic Deep Brain Stimulation in Parkinson's Disease Models

Advanced Healthcare Materials, EarlyView.
ABSTRACT Magnetogenetic deep brain stimulation (MG‐DBS) represents a wireless neuromodulation that has demonstrated long‐lasting behavioral benefits in Parkinson's disease models. However, the circuit‐level mechanisms underlying these therapeutic effects have remained uncharacterized due to limitations of conventional neural interfaces.
Jakyoung Lee, Yeongdo Lee, Enji Kim, Hunkyu Seo, Myoungjae Oh, Hanho Joo, Somin Lee, Jae‐Hyun Lee, Hyun Ho Jung, Minsuk Kwak, Jang‐Ung Park   +10 more
wiley   +1 more source

Mixed-mode fracture of notched AW 2099-T83 Al-Li Alloy: Effects of inclination angle and stress triaxiality

Results in Engineering
Third-generation aluminum-lithium alloys such as AW 2099-T83 offer attractive properties for aerospace applications, including low density, high stiffness, and excellent fracture toughness.
Jafar Albinmousa
doaj   +1 more source

Paraprotella saltatrix, a new species of the Caprellidea (Crustacea: Amphipoda) from Phuket Island, Thailand [PDF]

, 2002
Paraprotella saltatrix sp. nov. is described from specimens from Phuket Island, the Andaman Sea coast of Thailand. Paraprotella saltatrix differs from P.
Guerra García, José Manuel, Takeuchi, Ichiro   +1 more
core  

Common Signatures of Altered Gene Regulation and Invasiveness of Different Breast Cancer Cell Lines after Matrix Interface Crossing

Advanced Healthcare Materials, EarlyView.
Interface transmigration reprograms triple‐negative breast cancer cells, triggering a shared switch toward more aggressive and invasive phenotypes. Using a collagen I interface model, this study identifies shared transcriptional changes involving proliferation, chromatin remodeling, and DNA repair pathways.
Cornelia Clemens, Hannah Trampert, Nataliia Kotsiuba, Tilo Pompe   +3 more
wiley   +1 more source

A compact wide slot antenna with dual band-notch characteristic for ultra wideband applications

Journal of Microwaves, Optoelectronics and Electromagnetic Applications
A compact CPW-fed ultra-wideband antenna with dual band-notch characteristic is presented. Two notched frequency bands are obtained by embedding two U-shaped slots in the radiation patch and a rectangle slot in the ground plane. The two notched bands can
Cheng-yuan Liu, Tao Jiang, Ying-song Li
doaj   +1 more source

Effects of Notch Misalignment and Tip Radius on Displacement Field in V-Notch Rail Shear Test as Determined by Photogrammetry [PDF]

Evolution of the 3D strain field during ASTM-D-7078 v-notch rail shear tests on 8-ply quasi-isotropic carbon fiber/epoxy laminates was determined by optical photogrammetry using an ARAMIS system.
Hill, Charles S., Oliveras, Ovidio M.
core   +1 more source