Results 41 to 50 of about 3,263,406 (307)

Molecular genetic analysis of a "sine oculis" enhancer and the "leventina" gene as a model system to study human macular degeneration in "Drosophila" [PDF]

, 2004
The leventina gene as a model system to study human macular degeneration in Drosophila. Age-related macular degeneration (AMD) is one of the most frequent reasons for blindness of the elderly people and accounts for approximately 50% of registered ...
Pauli, Tobias Samuel
core   +1 more source

Strain rate concentration factor in comparison with stress concentration factor of a circumferential notch in a round bar specimen

Nihon Kikai Gakkai ronbunshu, 2017
High-speed tensile testing is now being recognized as a standard testing method for evaluating the impact strength of engineering materials. The impact speeds of Izod and Charpy tests cannot be controlled and therefore do not correspond to the real ...
Nao-Aki NODA, Daichi AKAGI, Yunong SHEN, Rei TAKAKI, Tomohiro IKEDA, Yoshikazu SANO, Yasushi TAKASE   +6 more
doaj   +1 more source

Transcriptional program of osteoblast differentiation : coordinated activation of Notch, Wnt, and TGF-[beta] signaling pathways in MC3T3 cell line [PDF]

, 2005
In order to examine the early events in osteoblast differentiation, three different model systems for osteoblast differentiation were compared: mouse pre-osteoblastic cell line MC3T3; mouse myoblastic cell line C2C12 and primary mouse calvarial ...
Zamurovic, Natasa
core   +1 more source

Morphological Variations of Distal End of Femur: A Cross-sectional Study

International Journal of Anatomy Radiology and Surgery, 2022
Introduction: Apart from intercondylar notch and trochlear groove, the intercondylar line also contributes to knee joint instability. Knowledge of morphological variations of these anatomical landmarks can help in diagnosis as well as planning the ...
Jatin B Goda, Shailesh M Patel, Ajay M Parmar   +2 more
doaj   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

Delta-like 4 is indispensable in thymic environment specific for T cell development. [PDF]

, 2008
The thymic microenvironment is required for T cell development in vivo. However, in vitro studies have shown that when hematopoietic progenitors acquire Notch signaling via Delta-like (Dll)1 or Dll4, they differentiate into the T cell lineage in the ...
Holländer, Georg, Habu, S., Holländer, G. A., Hozumi, K., Hirano, K, Mailhos, C, Ken-ichi Hirano, Negishi, N, Saulius Zuklys, Habu, S, Zuklys, S, Yahata, T., Sonoko Habu, Mailhos, C., Georg A. Holländer, Naoko Negishi, Ando, K., Ando, K, Kiyoshi Ando, Holländer, GA, Shima, D. T., Negishi, N., Carolina Mailhos, Hozumi, K, Yahata, T, Shima, DT, Hirano, K., Katsuto Hozumi, Takashi Yahata, David T. Shima, Zuklys, S.   +30 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A study of Notch signalling in developmental angiogenesis [PDF]

, 2009
Blood vessel patterning during angiogenesis is a guided process. Endothelial tip cells located at the end of vascular sprouts are important for vessel guidance.
Phng, L.-K., Phng, L-K
core  

The role of NOTCH2 gene in human malignant glial brain tumours [PDF]

, 2008
Background: Glioblastoma multiforme (GBM), astrocytoma (A) and oligodendroglioma (OG) are the neoplasms of the glial lineage in the Central Nervous System (CNS).
Sivasankaran, Balasubramanian
core   +1 more source

Evaluation of ductile-brittle transition temperature of anisotropy material by small punch test with U-shaped notch

Ubiquity Proceedings, 2018
Miniature and standard specimens, were cut from the anisotropy materials with axial, central and radial directions to study the mechanical property. In the paper, main research focused on the small punch test (SPT) with un-notched and U-shaped notched ...
K. Guan, D. Wang, J. Dobrovska, K. Matocha   +3 more
doaj   +1 more source