Results 51 to 60 of about 44,552 (307)

Comparison of Ductile-to-Brittle Transition Behavior in Two Similar Ferritic Oxide Dispersion Strengthened Alloys [PDF]

, 2016
The ductile-to-brittle transition (DBT) behavior of two similar Fe-Cr-Al oxide dispersion strengthened (ODS) stainless steels was analyzed following the Cottrell–Petch model.
Aranda, M. M., Capdevila, Carlos, Chao, Jesús, González-Carrasco, José Luis, Rementería, Rosalía   +4 more
core   +5 more sources

Brittle fracture of U-notched graphite plates under mixed mode loading

Materials & Design, 2012
Abstract Brittle fracture of isostatic polycrystalline graphite is studied experimentally, theoretically and numerically using U-notched samples under mode I and mixed mode loading (I + II) considering different combinations of the notch radius and the tilt angle of the notch.
Berto F., Lazzarin P., Marangon C.
openaire   +3 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Coupling Finite Element Analysis and the Theory of Critical Distances to Estimate Critical Loads in Al6060-T66 Tubular Beams Containing Notches

Metals, 2020
This paper validates a methodology for the estimation of critical loads in tubular beams containing notch-type defects. The methodology is particularized for the case of Al6060-T66 tubular cantilever beams containing U-shaped notches.
Marcos Sánchez, Sergio Cicero, Borja Arroyo, José Alberto Álvarez   +3 more
doaj   +1 more source

Numerical predictions of U-notched sample failure based on a discrete energy argument [PDF]

Theoretical and Applied Fracture Mechanics, 2019
Abstract Kodsi (2016) proposed a criterion for isotropic, linear elastic media in a brittle state applicable to both sharp and blunt notches. Fracture toughness and material strength are the only parameters required to operate the criterion. This paper provides a formulation of the criterion specific to blunt notches and further examines the ...
Zahedi, S.A., Kodsi, C., Berto, F.
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Differential expression of Snail1 transcription factor and Snail1-related genes in alveolar and embryonal rhabdomyosarcoma subtypes [PDF]

, 2010
Rhabdomyosarcoma (RMS) represents the most common sarcoma of soft tissue among children. Two main RMSsubtypes are alveolar (ARMS) and embryonal (ERMS). The major goal of this study was to find differentially expressedgenes between RMS subtypes that could
Danuta Jarocha, Ewa Lukasiewicz, Katarzyna Miekus, Marcin Majka, Miroslawa Püsküllüoglu   +4 more
core   +3 more sources

Fracture assessment of U-notched graphite specimens by means of cohesive zone model

Procedia Structural Integrity, 2020
Abstract Various types of graphite have gained interest in many industrial applications due to their high strength and excellent heat tolerance. However, due to the brittle nature of this material, presence of stress concentrators such as notches and geometrical discontinuities considerably re-duces the overall loading bearing of the graphite ...
N. Razavi, H.R. Majidi, F. Berto, M.R. Ayatollahi   +3 more
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Experimental verification of the virtual isotropic material concept for the last-ply-failure of U-notched quasi-isotropic E-glass/epoxy composite laminates under tension-shear loading

Journal of Industrial Textiles, 2022
Fracture investigation of U-notched E-glass/epoxy laminated composite specimens with various notch root radii is performed under mixed mode I/II loading conditions both experimentally and theoretically.
Ali Reza Torabi, Ebrahim Pirhadi
doaj   +1 more source