Results 61 to 70 of about 4,533,013 (299)

A Study on the Morphology of the Suprascapular Notch and Its Distance from the Glenoid Cavity [PDF]

Journal of Clinical and Diagnostic Research, 2013
Introduction: A suprascapular nerve entrapment can occur at the suprascapular notch or at the spinoglenoid notch. So, the size and shape of the suprascapular notch are associated with suprascapular entrapment neuropathy as well as with an injury to ...
Muralidhar Reddy Sangam, Sattiraju Sri Sarada Devi, Karumanchi Krupadanam, Kolla Anasuya   +3 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Failure configuration and evaluation of hybrid CFRP-GFRP laminates using innovative Arcan fixture: Experimental and simulation approach

Composites Part C: Open Access
This study successfully explored and evaluated the impact of notches modification in U, V, and square shapes on both tensile and shear strength using Arcan fixture.
Ariyana Dwiputra Nugraha, Daffa Alandro, Kevin Gausultan Hadith Mangunkusumo, Muhammad Kusni, Yi Chieh Wu, Muhammad Akhsin Muflikhun   +5 more
doaj   +1 more source

Evaluation of anterior cruciate ligament injury and intercondylar notch stenosis in patients with knee osteoarthritis with MRI

Van Tıp Dergisi, 2020
INTRODUCTION: We aimed to evaluate intercondylar notch morphology of femur in patients with knee osteoarthritis (OA) and to investigate the relation of anterior cruciate ligament (ACL) injury.
Ayşe Serap Akgün
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Selective targeting of NOTCH-1 for therapeutic purposes in xenograft models of T-acute lymphoblastic leukemia [PDF]

, 2013
T-cell acute lymphoblastic leukemia (T-ALL) is an heterogeneous disease, characterized by several genetic alterations and polymorphic clinical features both in children and adults.
Agnusdei, Valentina
core  

Spatiotemporal oscillations of Notch1, Dll1 and NICD are coordinated across the mouse PSM [PDF]

, 2014
During somitogenesis, epithelial somites form from the pre-somitic mesoderm (PSM) in a periodic manner. This periodicity is regulated by a molecular oscillator, known as the 'segmentation clock', that is characterised by an oscillatory pattern of gene ...
Dale, J. Kim, Bone, Robert A., Appleton, Paul L., Wiedermann, Guy, Ferjentsik, Zoltan, Murray, Philip J., Bailey, Charlotte S. L., Maroto, Miguel   +7 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Congenital diseases caused by defective O-glycosylation of Notch receptors [PDF]

, 2018
2018-08The Notch signaling pathway is highly conserved and essential for animal development. It is required for cell differentiation, survival, and proliferation. Regulation of Notch signaling is a crucial process for human health.
Okajima, Tetsuya, Tashima, Yuko
core   +1 more source

Coupling Finite Element Analysis and the Theory of Critical Distances to Estimate Critical Loads in Al6060-T66 Tubular Beams Containing Notches

Metals, 2020
This paper validates a methodology for the estimation of critical loads in tubular beams containing notch-type defects. The methodology is particularized for the case of Al6060-T66 tubular cantilever beams containing U-shaped notches.
Marcos Sánchez, Sergio Cicero, Borja Arroyo, José Alberto Álvarez   +3 more
doaj   +1 more source