Results 81 to 90 of about 3,263,406 (307)
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Notch2 signaling in development and cancer [PDF]
Notch signaling via cell to cell interaction is a key mechanism in regulating proliferation, cell fate decisions and survival of various cell types in both invertebrates and vertebrates.
Tchorz, Jan Stephan
core +1 more source
Fracture investigation of U-notched E-glass/epoxy laminated composite specimens with various notch root radii is performed under mixed mode I/II loading conditions both experimentally and theoretically.
Ali Reza Torabi, Ebrahim Pirhadi
doaj +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Effects of Edentulism on Mandibular Morphology: Evaluation of Panoramic Radiographs
Purpose. The objective of this study was to evaluate morphological changes of the mandible in edentulous and dentate subjects using panoramic radiographs. Materials and Methods. Panoramic radiographs were divided into the following three groups: Group I (
Rıdvan Okşayan +5 more
doaj +1 more source
Fracture assessment of U-notched graphite specimens by means of cohesive zone model
Abstract Various types of graphite have gained interest in many industrial applications due to their high strength and excellent heat tolerance. However, due to the brittle nature of this material, presence of stress concentrators such as notches and geometrical discontinuities considerably re-duces the overall loading bearing of the graphite ...
N. Razavi +3 more
openaire +1 more source
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu +10 more
wiley +1 more source
Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani +10 more
wiley +1 more source
Systematic review on morphometric study of suprascapular notch
Suprascapular notch roofed by STSL is located in the lateral part of the superior border of scapula and medial to the base of the coracoids process. The suprascapular nerve (SN) is entrapped due to anatomical variation of the notch.
Sushma Daripelli +2 more
doaj +1 more source
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu +7 more
wiley +1 more source

