Results 81 to 90 of about 4,877,471 (257)

Uranium-lead dating method at the Pará-Iso isotope geology laboratory, UFPA, Belém - Brazil

open access: yesAnais da Academia Brasileira de Ciências, 2007
Analytical procedures for U-Pb isotope dilution analyses at the Pará-Iso isotope geology laboratory of the Federal University of Pará (UFPA) are described in detail. The procedures are applied to zircon, titanite, rutile, apatite, columbite-tantalite and
Robert S. Krymsky   +3 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Lost in the Vaso‐Occlusion: A Patient's Abdominal Pain Returns With a Vengeance

open access: yes
Pediatric Blood &Cancer, EarlyView.
Dunia Hatabah   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

T-t Evolution of the Early Proterozoic Rocks in the Northern Ladoga Region from the Data on U-Pb, Rb-Sr and Sm-Nd Systems in Minerals

open access: yesГеодинамика и тектонофизика
This paper presents the results of a study of isotopic systems in minerals and rocks in southern margin of the epi-Archean Karelian craton in the zone of its junction with the Svecofennian mobile belt.
Sh. K. Baltybaev   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

THE AGE OF EARLY COLLISIONAL GRANITOIDS OF WESTERN SANGILEN (SE TUVA): IMPLICATIONS FOR ESTIMATING THE DURATION OF OROGENY AT THE MARGIN OF THE TUVA-MONGOLIAN MASSIF

open access: yesГеодинамика и тектонофизика
The first U-Pb isotope-geochronological data were obtained on the age of early collisional granitoids of the Matut massif (Western Sangilen, SE Tuva).
D. V. Semenova   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

S1: U–Pb Methodology. Detrital zircon U–Pb insights into the timing and provenance of the South Pyrenean Jaca Basin

open access: yes, 2019
Supplementary material 1: Extended Zircon U–Pb LA–ICP–MS methodology.
Roigé, M.   +5 more
openaire   +1 more source

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