Results 91 to 100 of about 468,322 (270)
, 2016 We consider the problem of performing predecessor searches in a bounded universe while achieving query times that depend on the distribution of queries.
Bose, Prosenjit +3 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
A Conceptual Framework Proposal for a Noise Modelling Service for Drones in U-Space Architecture. [PDF]
Int J Environ Res Public Health, 2021 Langen T, Nunavath V, Dahle OH.
europepmc +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Flavored resonant leptogenesis in the U(1)X model
Nuclear Physics BWe study the generation of baryon asymmetry through the flavored resonant leptogenesis in the U(1)X extension of the Standard Model. Being a generalization of the U(1)B-L, U(1)X is an ultraviolet-complete model of the right-handed neutrinos (RHNs), whose
Garv Chauhan
doaj +1 more source
A Tactical Conflict Resolution Proposal for U-Space Zu Airspace Volumes. [PDF]
Sensors (Basel), 2021 Jover J, Bermúdez A, Casado R.
europepmc +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Double-dual types over the Banach space C(K)
International Journal of Mathematics and Mathematical Sciences, 2005 Let K be a compact Hausdorff space and C(K) the Banach space of all real-valued continuous functions on K, with the sup-norm. Types over C(K) (in the sense of Krivine and Maurey) can be uniquely represented by pairs (ℓ,u) of bounded real-valued functions
Markus Pomper
doaj +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source