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Concept of Separation Management for UAS in the U-space

, 2022
This document describes the Concept of Operations (ConOps) of a separation management service in the U-space. The document contains the final version of the ConOps developed to capture the conclusions drawn from the BUBBLES workshops, as well as from the validation exercises and to define BUBBLES as a SESAR solution, following the indications provided ...
Claramunt-Puchol, Cecilia, Vera-Vélez, Norberto, Balbastre-Tejedor, Juan Vicente   +2 more
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Remark on the Cauchy problem for the evolution p-Laplacian equation

Journal of Inequalities and Applications, 2017
In this paper, we prove that the semigroup S ( t ) $S(t)$ generated by the Cauchy problem of the evolution p-Laplacian equation ∂ u ∂ t − div ( | ∇ u | p − 2 ∇ u ) = 0 $\frac{\partial u}{\partial t}-\operatorname{div}(|\nabla u|^{p-2}\nabla u)=0$ ( p > 2
Liangwei Wang, Jngxue Yin, Jinde Cao
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Low Altitude Airspace: how enterprises discover a new business dimension

GEOmedia, 2019
The development of Low Altitude Airspace activities is a great opportunity for many companies. Work carried out by drones (inspections, surveillance and control, mapping etc.) will be supported by other new activities and services that will pave the way ...
Chiara Mozzetti, Alberto Devitis
doaj  

First Detection of X-Ray Polarization in Galactic Ultraluminous X-Ray Pulsar Swift J0243.6+6124 with IXPE

The Astrophysical Journal Letters
We report the results of first ever spectropolarimetric analyses of the Galactic ultraluminous X-ray pulsar Swift J0243.6+6124 during the 2023 outburst using quasi-simultaneous IXPE, NICER, and NuSTAR observations.
Seshadri Majumder, Rwitika Chatterjee, Kiran M. Jayasurya, Santabrata Das, Anuj Nandi   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

AstroSat View of the Neutron Star Low-mass X-Ray Binary GX 5-1

The Astrophysical Journal
We present the spectral and timing study of the bright neutron star low-mass X-ray binary GX 5-1 using AstroSat/Large Area X-ray Proportional Counter (LAXPC) and Soft X-ray Telescope observations conducted in 2018.
V. P. Shyam Prakash, Vivek K. Agrawal
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source