Results 51 to 60 of about 4,461,121 (140)

Proteomic level changes associated with S3I201 treated U87 glioma cells

, 2017
Glioblastoma multiforme is Grade IV brain tumor associated with high mortality and limited therapeutics. Signal Transducer and Activator of Transcription 3 (STAT3) is persistently active in several cancers including gliomas, and plays a major role in ...
JAIN, R, ATAK, A, YEOLA, A, SRIVASTAVA, S   +3 more
core   +1 more source

ERN1 modifies the effect of glutamine deprivation on tumor growth related factors expression in U87 glioma cells [PDF]

, 2018
The expression of a subset of genes encoding important tumor growth related factors in U87 glioma cells with ERN1 (endoplasmic reticulum to nucleus signaling 1) loss of function as well as upon glutamine deprivation was studied.
A. Y. Kuznetsova, I. V. Kryvdiuk, O. S. Hnatiuk, A. P. Kharkova, O. H. Minchenko, O. Y. Luzina   +5 more
core   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

Efeito dos glicosaminoglicanos (GAGs) sobre a progressão do glioma C6: abordagens in vitro e in vivo / [PDF]

, 2001
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas.O presente estudo tem por objetivo verificar efeitos dos glicosaminoglicanos sobre a adesão in vitro do glioma C6.
Soares, Bruno Lobão
core  

Natural product‐derived TRPM7 channel inhibitors in neurological injury: Mechanisms, pharmacological potential and translational challenges

British Journal of Pharmacology, EarlyView.
Disruption of intracellular ionic homeostasis is a convergent pathological feature across diverse neurological injuries and disorders, including ischaemic and haemorrhagic stroke, hypoxic–ischaemic brain injury, traumatic brain injury, epilepsy and brain tumour.
Xinyang Zhang, Hio Lam Ho, F. David Horgen, Andrea Fleig, Zhong‐Ping Feng, Hong‐Shuo Sun   +5 more
wiley   +1 more source

NOTCH3 knockdown in U87-MG cells represses glioma cells growth and hinders cell migration and invasion.

, 2013
(A) Cell viabilities of U87-MG and U251-MG cells following NOTCH3 knockdown were determined using MTT assay. The data represent mean ± SE of three independent experiments performed in triplicate.
Timothy C. Ryken (413028), Mahfoud Assem (413029), Mohammad A. Y. Alqudah (413026), Zita A. Sibenaller (413027), Maha S. Al-Keilani (413025), Supreet Agarwal (413024)   +5 more
core   +1 more source

Expression of ubiquitin specific peptidase and ATG7 genes in U87 glioma cells upon glutamine deprivation [PDF]

, 2017
We have studied the effect of glutamine deprivation on the expression of genes encoding for ubiquitin specific peptidases (USP) and ubiquitin activating enzyme E1-like protein/autophagy related 7 (GSA7/ATG7) in U87 glioma cells in relation to inhibition ...
О. O. Ratushna, V. V. Telychko, О. O. Riabovol, D. O. Minchenko, O. V. Halkin, O. H. Minchenko   +5 more
core   +1 more source

Evidence That the Protein Phosphatase Activity of PTEN Contributes to Embryonic Development and Tumor Suppression

Cancer Science, EarlyView.
Mice expressing only mutant PTEN Y138L, a protein which shows normal suppression of cellular AKT yet lacks protein phosphatase activity, die in utero, and heterozygous mice display a range of tumors. This indicates both the lipid and protein phosphatase activities of PTEN work together for normal tumor suppression and embryonic development.
Priyanka Tibarewal, Laura Spinelli, Nisha Kriplani, Helen Wise, Nadege Poncet, Giulia Marzano, Karen E. Anderson, Katarzyna M. Grzes, Zofia Varyova, Mahreen Adil, C. Peter Downes, Phillip T. Hawkins, Len R. Stephens, Kate G. Storey, Doreen A. Cantrell, Bart Vanhaesebroeck, Nicholas R. Leslie   +16 more
wiley   +1 more source

The Imbalance Between Tumor Immunosurveillance and Tumor Immune Escape in Glioblastoma

Immunology &Cell Biology, EarlyView.
(Left)The identification and elimination of tumour cells is enabled by the infiltration of functional innate and adaptive immune effectors into the TME, such as natural killer cells (NK cells) and cytotoxic T cells (CD8 T cells). Effective innate and adaptive immune responses facilitate immunological control of malignant outgrowth.
Sarah J. MacDonald, Matthew Drill, Padmakrishnan C. Jayakrishnan, Richard P. Sequeira, Terence J. O'Brien, Rosalind L. Jeffree, Mastura Monif   +6 more
wiley   +1 more source

The establishment of U87 glioma sphere cell invasion model in zebrafish embryos.

, 2013
A. Dual color confocal image shows that U87 sphere cells (RFP labeled, red) were microinjected into the middle of yolk sac within Tg (fli1:EGFP)y1 transgenic zebrafish embryos (EGFP labeled, green). B.
Ai Gu (402604), Ting-ting Li (3429137), Xia Zhang (41398), Xiu-wu Bian (134899), Xiao-jun Yang (402603), Shi-cang Yu (402605), Chuan Xu (293667), Wei Cui (92129), You-hong Cui (402606)   +8 more
core   +1 more source