Results 31 to 40 of about 23,643 (220)

miR-107 inhibits the proliferation, migration and invasion of glioma cells in vitro [PDF]

Jichu yixue yu linchuang, 2020
Objective To investigate the regulation mechanism of miR-107 on proliferation, migration and invasion of glioma cells. Methods RT-qPCR was used to detect the expression of miR-107 and FOXK1 in human normal astrocytes NHA, glioma cell lines U87, A172 and ...
SUN Mao-cang, LI Xin
doaj  

RETRACTED: miRNA-193a-3p Regulates the AKT2 Pathway to Inhibit the Growth and Promote the Apoptosis of Glioma Cells by Targeting ALKBH5

Frontiers in Oncology, 2021
Emerging evidence indicates that microRNA (miR)-193a-3p is involved in the tumor progression of various cancers. However, the biological functions and precise molecular mechanisms of miR-193a-3p in gliomas have not been well documented. Accordingly, this
Yong Cui, Yong Cui, Qi Wang, Jing Lin, Lei Zhang, Chi Zhang, Huairui Chen, Jun Qian, Chun Luo   +8 more
doaj   +1 more source

IDH1^R132HMutation Increases U87 Glioma Cell Sensitivity to Radiation Therapy in Hypoxia [PDF]

BioMed Research International, 2014
Objective.IDH1codon 132 mutation (mostly Arg132His) is frequently found in gliomas and is associated with longer survival. However, it is still unclear whetherIDH1mutation renders the cell more vulnerable to current treatment, radio- and chemotherapy.Materials and Methods.
Wang, Xiao-Wei, Labussière, Marianne, Valable, Samuel, Pérès, Elodie A., Guillamo, Jean-Sébastien, Bernaudin, Myriam, Sanson, Marc   +6 more
openaire   +4 more sources

The Potential Roles of Long Noncoding RNAs (lncRNA) in Glioblastoma Development [PDF]

, 2016
Long noncoding RNA (lncRNA) may contribute to the initiation and progression of tumor. In this study, we first systematically compared lncRNA and mRNA expression between glioblastoma and paired normal brain tissues using microarray data.
Eischen, Christine M., Fan, Wenhong, Liu, Shuang, Mitra, Ramkrishna, Yin, Feng, Zhao, Ming-Ming, Zhao, Zhongming   +6 more
core   +2 more sources

Glioma-derived exosomes drive the differentiation of neural stem cells to astrocytes.

PLoS ONE, 2020
Exosomes appear to be effective inter-cellular communicators delivering several types of molecules, such as proteins and RNAs, suggesting that they could influence neural stem cell (NSC) differentiation.
Krishna D Sharma, Danielle Schaal, Rajshekhar A Kore, Rabab N Hamzah, Sahitya Chetan Pandanaboina, Abdallah Hayar, Robert J Griffin, Malathi Srivatsan, Nathan S Reyna, Jennifer Yanhua Xie   +9 more
doaj   +1 more source

OASIS/CREB3L1 is induced by endoplasmic reticulum stress in human glioma cell lines and contributes to the unfolded protein response, extracellular matrix production and cell migration. [PDF]

PLoS ONE, 2013
OASIS is a transcription factor similar to ATF6 that is activated by endoplasmic reticulum stress. In this study we investigated the expression of OASIS in human glioma cell lines and the effect of OASIS knock-down on the ER stress response and cell ...
Ravi N Vellanki, Liling Zhang, Allen Volchuk   +2 more
doaj   +1 more source

The nitric oxide donor JS-K sensitizes U87 glioma cells to repetitive irradiation [PDF]

Tumor Biology, 2017
As a potent radiosensitizer nitric oxide (NO) may be a putative adjuvant in the treatment of malignant gliomas which are known for their radio- and chemoresistance. The NO donor prodrug JS-K (O2-(2.4-dinitrophenyl) 1-[(4-ethoxycarbonyl) piperazin-1-yl] diazen-1-ium-1,2-diolate) allows cell-type specific intracellular NO release via enzymatic activation
Heckler, Max, Osterberg, Nadja, Günzle, Jessica, Thiede-Stan, Nina Kristin, Reichardt, Wilfried, Weidensteiner, Claudia, Saavedra, Joseph E., Weyerbrock, Astrid   +7 more
openaire   +4 more sources

Focused ultrasound-enabled brain tumor liquid biopsy [PDF]

, 2018
Although blood-based liquid biopsies have emerged as a promising non-invasive method to detect biomarkers in various cancers, limited progress has been made for brain tumors.
Chen, Hong, Cheng, Galen, Dunn, Gavin P., Leuthardt, Eric C., Liu, Weijun, Nazeri, Arash, Petti, Allegra A., Wang, Xiaowei, Ye, Dezhuang, Yue, Yimei, Zhu, Lifei   +10 more
core   +3 more sources

ROS-Mediated Cytotoxic Effect of Copper(II) Hydrazone Complexes against Human Glioma Cells

Molecules, 2014
2-Acetylpyridine acetylhydrazone (H2AcMe), 2-benzoylpyridine acetylhydrazone (H2BzMe) and complexes [Cu(H2AcMe)Cl2] (1) and [Cu(H2BzMe)Cl2] (2) were assayed for their cytotoxicity against wild type p53 U87 and mutant p53 T98 glioma cells, and against MRC-
Angel A. Recio Despaigne, Jeferson G. Da Silva, Pryscila R. da Costa, Raquel G. dos Santos, Heloisa Beraldo   +4 more
doaj   +1 more source

Proton beam irradiation stimulates migration and invasion of human U87 malignant glioma cells [PDF]

Journal of Radiation Research, 2013
Migration and invasion of malignant glioma play a major role in tumor progression and can be increased by low doses of gamma or X-ray irradiation, especially when the migrated tumor cells are located at a distance from the main tumor mass or postoperative cavity and are irradiated in fractions.
Zaboronok, Alexander, Isobe, Tomonori, Yamamoto, Tetsuya, Sato, Eisuke, Takada, Kenta, Sakae, Takeji, Tsurushima, Hideo, Matsumura, Akira   +7 more
openaire   +2 more sources