Monoclonal antibodies against human astrocytomas and their reactivity pattern [PDF]
The establishment of hybridomas after fusion of X63-Ag8.653 mouse myeloma cells and splenocytes from mice hyperimmunized against human astrocytomas is presented. The animals were primed with 5 × 106 chemically modified uncultured or cultured glioma cells.
Eisenmenger, Wolfgang +8 more
core +1 more source
Short-term effects of shikonin on the cellular viability of C6 and U87 glioma cells.
MTT assay showed that the viability of C6 (A) and U87 (B) glioma cells decreased in a dose dependent manner when incubated 3 hours with shikonin.
Chuanjiang Huang (428570) +6 more
core +1 more source
Resveratrol represses YKL-40 expression in human glioma U87 cells [PDF]
Background Glioblastoma multiforme (GBM) is the most malignant intracranial tumour that develops in both adults and children. Microarray gene analyses have confirmed that the human YKL-40 gene is one of the most over-expressed genes in these ...
Keisuke Miyake +9 more
core +1 more source
The schema of the effects of artemether and shRNA-VCAM-1 on the U87 human glioma cells.
The schematic diagram demonstrates the effects of artemether and shRNA-VCAM-1 on the malignant behavior of U87 human glioma cells. The combination of artemether with shRNA-VCAM-1 shows a synergistic inhibitory effect on the malignancy of glioma cells by ...
Yi Hu (58993) +7 more
core +1 more source
Inhibition of IRE1 modifies the hypoxic regulation of GADD family gene expressions in U87 glioma cells [PDF]
We have studied hypoxic regulation of the expression of genes encoded GADD (growth arrest and DNA damage) family proteins in U87 glioma cells in relation to inhibition of IRE1 (inositol requiring enzyme-1), which controls cell proliferation and tumor ...
I. V. Kryvdiuk +5 more
core +2 more sources
Objective. The aim of the present investigation was to study the expression of genes encoding homeobox proteins ZEB2 (zinc finger E-box binding homeobox 2), TGIF1 (TGFB induced factor homeobox 1), SPAG4 (sperm associated antigen 4), LHX1 (LIM homeobox 1),
Rudnytska Olha V. +8 more
core +1 more source
Expression of tumor growth related genes in IRE1 knockdown U87 glioma cells: effect of hypoxia [PDF]
We have studied the effect of IRE1 signaling enzyme knockdown as well as hypoxia on the expression of genes encoding the important tumor growth related proteins (BRCA1, DEK, BCL2L1, COL6A1, TPD52, HOMER3, and GNPDA1) in U87 glioma cells.
O. O. Ratushna +5 more
core +1 more source
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum +5 more
wiley +1 more source
Overexpression of MnSOD, but not CAT, blocks DCEF-induced directional migration of U87 glioma cells.
ROS generation in cells stimulated by an EF with a strength of 200 mV/mm 0, 15, 30, and 60 minutes with or without overexpression of MnSOD or mCAT, as detected by DCFH-DA (A) or HE (B).
Tunan Chen (402765) +5 more
core +1 more source
Effect of hypoxia on the expression of nuclear genes encoding mitochondrial proteins in U87 glioma cells [PDF]
We have studied the effect of hypoxia on the expression of nuclear genes encoding mitochondrial proteins in U87 glioma cells under the inhibition of IRE1 (inositol requiring enzyme-1), which controls cell proliferation and tumor growth as a central ...
О. O. Ratushna +4 more
core +2 more sources

