Results 11 to 20 of about 4,461,121 (140)

Exosomal miRNA-21 from Toxoplasma gondii-infected microglial cells induces the growth of U87 glioma cells by inhibiting tumor suppressor genes [PDF]

Sci Rep, 2022
Toxoplasma gondii is an intracellular protozoan parasite that can modulate the microenvironment of infected hosts and is known to be associated with the incidence of brain tumor growth.
Jung, Bong-Kwang, Song, Hyemi, Shin, Hyejoo, Chai, Jong-Yil   +3 more
core   +2 more sources

Quantifying Deformation and Migration Properties of U87 Glioma Cells Using Dielectrophoretic Forces [PDF]

Biosensors (Basel), 2022
Glioblastoma multiforme is one of the most aggressive malignant primary brain tumors. To design effective treatment strategies, we need to better understand the behavior of glioma cells while maintaining their genetic and phenotypic stability.
Elitas, Meltem, Beyzanur Ozogul, Sumeyra Vural Kaymaz, Islam, Monsur, Korvink, Jan G., Ozogul, Beyzanur, Pouya Sharbati, Kaymaz, Sumeyra Vural, Sharbati, Pouya, Meltem Elitas, Jan G. Korvink, Monsur Islam, Esra Sengul, Vural Kaymaz, Sümeyra, Sengul, Esra   +14 more
core   +2 more sources

Single-cell mechanophenotyping in microfluidics to evaluate behavior of U87 glioma cells [PDF]

Micromachines (Basel), 2020
Integration of microfabricated, single-cell resolution and traditional, population-level biological assays will be the future of modern techniques in biology that will enroll in evolution of biology into a precision scientific discipline.
Şengül, Esra, Meltem Elitas, Elitaş, Meltem, Esra Sengul   +3 more
core   +2 more sources

Analysis of U87 glioma cells by dielectrophoresis

Electrophoresis, 2022
Glioblastoma multiforme is the most aggressive and invasive brain cancer consisting of genetically and phenotypically altering glial cells. It has massive heterogeneity due to its highly complex and dynamic microenvironment.
Pouya Sharbati, Şengül, Esra, Sharbati, Pouya, Meltem Elitas, Jan G. Korvink, Monsur Islam, Elitaş, Meltem, Islam, Monsur, Esra Sengul, Korvink, Jan G.   +9 more
core   +2 more sources

Metabolic impact of anti-angiogenic agents on U87 glioma cells. [PDF]

PLoS ONE, 2014
BACKGROUND: Glioma cells not only secrete high levels of vascular endothelial growth factor (VEGF) but also express VEGF receptors (VEGFR), supporting the existence of an autocrine loop. The direct impact on glioma cells metabolism of drugs targeting the
Ocvirk Janja, Mesti Tanja, Laurence Le Moyec, Le Moyec Laurence, Janja Ocvirk, Triba Mohamed N., Ocvirk, Janja, Mesti, Tanja, Savarin, Philippe, Carpentier, Antoine, F, Mohamed N Triba, Tanja Mesti, Carpentier Antoine F., Le Moyec, Laurence, Antoine F Carpentier, Savarin Philippe, Triba, Mohamed, N, Philippe Savarin, Banissi, Claire, Carpentier, Antoine,, Claire Banissi, Banissi Claire, Triba, Mohamed,   +22 more
core   +2 more sources

TRAIL and Paclitaxel Synergize to Kill U87 Cells and U87-Derived Stem-Like Cells in Vitro

International Journal of Molecular Sciences, 2012
U87-derived stem-like cells (U87-SLCs) were cultured using serum-free stem cell media and identified by both biological behaviors and markers. Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and paclitaxel (PX), in combination or ...
Bo Qiu, Xiyang Sun, Shaowu Ou, Dongyong Zhang, Jun Tao, Yong Wang   +5 more
core   +2 more sources

POFUT1 Serves as an Independent Prognostic Factor and Therapeutic Target by Activating the PI3K/AKT Pathway in Glioma [PDF]

Brain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Objective Protein O‐fucosyltransferase 1 (POFUT1) has been implicated in several malignancies, but its functional and prognostic significance in glioma remains insufficiently defined. This study evaluated whether POFUT1 expression is associated with glioma progression, patient outcome, and PI3K/AKT pathway activity.
Kai Yang, Chunlei Ju, Yifan Wang, Aijie Guo, Xiaochen Yang, Yang Mi, Yifei Su, Chunhong Wang, Hongming Ji   +8 more
wiley   +2 more sources

QRICH1 Suppresses Glioma Progression by Inducing ER Stress and Activating the PERK‐ATF4‐CHOP Pathway [PDF]

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Background ER stress (ERS) influences tumor behavior through the unfolded protein response (UPR), yet its role in glioma is not fully defined. This study investigated the function of the ERS‐related regulator QRICH1 in glioma progression. Methods Public databases (TCGA and GTEx) were used to evaluate QRICH1 expression, survival, and prognostic
Yunjiang Wang, Min Xu, Zhenglou Chen, Xuqi Huo, Ya Xue, Xiang Ji, Yang Shen, Hongsheng Wang   +7 more
wiley   +2 more sources

Natural Compounds Targeting Oncogenic Signaling Networks in Glioblastoma: Molecular Mechanisms, Translational Advances, and Clinical Perspectives [PDF]

Brain and Behavior, Volume 16, Issue 9, September 2026.
Glioblastoma (GBM) is a highly aggressive brain tumor with a poor prognosis, driven by abnormal signaling pathways that promote growth and resistance to treatment. Conventional therapies are inadequate, highlighting the need for novel multitargeted approaches.
Mehrukh Zehravi, Md Abul Hassan, Md. Al Amin, Sherouk Hussein Sweilam, Jeetendra Kumar Gupta, Ramenani Hari Babu, Pericharla Venkata Narasimha Raju, Krishna Vamsi Kandimalla, Phanindra Erukulla, Patibandla Jahnavi, Rajeshwar Vodeti, Abdul Ajeed Mohathasim Billah, Safia Obaidur Rab, Sharuk L. Khan   +13 more
wiley   +2 more sources

Comparison of metabolite profiles in U87 glioma cells and mesenchymal stem cells

BioSystems, 2011
Gas chromatography-mass spectrometry (GC-MS) profiles were generated from U87 glioma cells and human mesenchymal stem cells (hMSC). 37 metabolites representing glycolysis intermediates, TCA cycle metabolites, amino acids and lipids were selected for a ...
Selbig, Joachim, Willmitzer, L., Selbig, J., Feher, K., Guo, K. T., Schichor, C., Guo, K., Ke-Tai Guo, Feher, Kristen, Schichor, Christian, Juerchott, Kathrin, Lothar Willmitzer, Kristen Feher, Jurchott, K., Willmitzer, Lothar (Prof.Dr), Kathrin Jürchott, Gareth Catchpole, Catchpole, Gareth, Catchpole, G., Guo, Ke-Tai, Christian Schichor, Joachim Selbig   +21 more
core   +2 more sources