Results 151 to 160 of about 66,565 (306)

Molecular basis and biological relevance of bacterial and plant pinoresinol/lariciresinol reductase specificities

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract A bacterial pinoresinol/lariciresinol reductase (PLR) homolog named NrPinZ was obtained from a Novosphingobium rhizosphaerae sp. LY bacterial strain, with NrPinZ being part of its 5‐step biochemical system catabolizing pinoresinol into coniferyl aldehyde and vanillin.
Clyde A. Smith   +7 more
wiley   +1 more source

Carboxydotrophic Acetogenesis in Alkaline Conditions Results in Transient Formate Production by the Halo‐Alkaliphilic Acetogen Haloacetibacter carboxydivorans Gen. Nov. sp. Nov

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 1, February 2026.
This work presents the physiological exploration of the halo‐alkaliphilic, carboxydotrophic acetogen bacterium MD4. In contrast to well‐characterised neutrophilic and slightly acidophilic acetogenic carboxydotrophs, this work shows an important role for formate production, instead of ethanol, as a redox exhaust mechanism in alkaline conditions ...
Martijn Diender   +5 more
wiley   +1 more source

Fasting as Medicine: Mitochondrial and Endothelial Rejuvenation in Vascular Aging

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Aging impairs cerebrovascular health by driving mitochondrial dysfunction, oxidative stress, endothelial failure, and neurovascular uncoupling, leading to BBB breakdown and cognitive decline. In contrast, time‐restricted feeding/eating counteracts these mechanisms by restoring mitochondrial function, activating adaptive nutrient‐sensing pathways ...
Madison Milan   +13 more
wiley   +1 more source

Phenotypes of Fission Yeast Defective in Ubiquinone Production Due to Disruption of the Gene for p -Hydroxybenzoate Polyprenyl Diphosphate Transferase

open access: green, 2000
Naonori Uchida   +6 more
openalex   +2 more sources

LAG‐3+ Regulatory T Cells Suppress Effector Function of T Cells and Allow Their Proliferation Into Regulatory T Cells

open access: yesImmunology, Volume 177, Issue 2, Page 317-328, February 2026.
LAG‐3+ regulatory T cells suppress the effector but not the proliferative response of naïve cognate antigen‐specific CD4+ T cells in vivo. The suppressed T cells display upregulation of immune checkpoints and downregulation of pro‐inflammatory pathways with enhanced TCR signaling and reduced oxidative metabolism.
Avijit Dutta   +7 more
wiley   +1 more source

From isolation to insights: mitochondrial complex I in the diatom Phaeodactylum tricornutum

open access: yesThe Plant Journal, Volume 125, Issue 3, February 2026.
SUMMARY Diatoms are among the most ecologically successful microalgae, contributing significantly to marine primary production and global carbon cycling. Their distinctive metabolic architecture, shaped by a complex evolutionary history involving secondary endosymbiosis, includes a highly compartmentalized cell organization and unique metabolic ...
Federico Berdun   +7 more
wiley   +1 more source

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