Results 261 to 270 of about 69,441 (293)

Ubiquinone and related compounds

Biochemical Medicine, 1973
Abstract UQ-10 in human blood could be determined by electron capture gas chromatography. In this chromatography, a part of UQ-10 was cyclized to UC-9 and the latter was twice as sensitive as the former. Chromanol compounds involving perhydroubichromanol-9 and α-tocopherol were similarly determined.
Isuke Imada, M. Toyoda, Hiroshi Morimoto, Yasuko Ashida, T. Amano   +4 more
openaire   +3 more sources

Ubiquinone accumulates in the mitochondria of yeast mutated in the ubiquinone binding protein, Qcr8p

Biochemical and Biophysical Research Communications, 2006
In Saccharomyces cerevisiae, the trans-membrane helix of Qcr8p, the ubiquinone binding protein of complex III, contributes to the Q binding site. In wild-type cells, residue 62 of the helix is non-polar (proline). Substitution of proline 62 with a polar, uncharged residue does not impair the ability of the cells to respire, complex III assembly is ...
Ann E. Hagerman, Richard A. Willis, Ruth A. Hagerman, Natashya J. Waring   +3 more
openaire   +3 more sources

Protein-Ubiquinone Interaction: Synthesis and Biological Properties of Ethoxy Ubiquinone Derivatives

Biochemistry, 1994
For investigation of the protein-ubiquinone interaction in the succinate-cytochrome c reductase region of the bovine heart mitochondrial electron-transport chain, ethoxy-substituted ubiquinone derivatives, 2-ethoxy-3-methoxy- or 3-ethoxy-2-methoxy-5-methyl-6-decyl-1,4-benzoquinone (EtOQ0C10) and 2,3-diethoxy-5-methyl-6-decyl-1,4-benzoquinone [(EtO ...
Da-Yan He, Linda Yu, Lian-Quan Gu, Chang-An Yu   +3 more
openaire   +3 more sources

Increased bioavailability of ubiquinol compared to that of ubiquinone is due to more efficient micellarization during digestion and greater GSH-dependent uptake and basolateral secretion by Caco-2 cells.

Journal of Agricultural and Food Chemistry, 2014
The oral bioavailability of ubiquinol recently has been reported to be greater than that of ubiquinone in healthy adults. The basis for this influence of redox state of coenzyme Q (CoQ) on bioavailability has been investigated using the coupled in vitro ...
M. Failla, C. Chitchumroonchokchai, Fumiki Aoki   +2 more
semanticscholar   +1 more source

An ubiquinone-binding protein in mitochondrial NADH-ubiquinone reductase (complex I)

Biochemical and Biophysical Research Communications, 1986
An ubiquinone-binding protein (QP) was purified from mitochondrial NADH-ubiquinone reductase (Complex I). Complex I was separated into 3 fragments: a fraction of hydrophobic proteins, that of soluble iron-sulfur protein (IP) and soluble NADH dehydrogenase of flavoprotein by a procedure involving the resolution with DOC and cholate, followed by ethanol ...
Takayuki Ozawa, Hiroshi Suzuki
openaire   +3 more sources

Effect of exogenous ubiquinone-10 on the ubiquinone pool of liver and spleen of mice

Biochimica et Biophysica Acta (BBA) - General Subjects, 1974
Abstract The ubiquinone content in liver and spleen of mice after single intravenous administration of 150 μg/mouse ubiquinone-10 emulsion was investigated. It was found that 1 day after this administration, there is significant increase in the total ubiquinone concentration in the liver and the spleen, which returns to control level 7 days later ...
Adria C. Casey, Emile G. Bliznakov
openaire   +3 more sources

Location and activity of ubiquinone 10 and ubiquinone analogs in model and biological membranes

Biochemistry, 1987
Deuteriated analogues of ubiquinone 10 (Q10) have been dispersed with plasma membranes of Escherichia coli and with the inner membranes of beetroot mitochondria. Orientational order at various deuteriated sites was measured by solid-state deuterium nuclear magnetic resonance (2H NMR).
L. E. Weir, A. Post, R. N. Robertson, P. W. Westerman, Max A. Keniry, Bruce Cornell   +5 more
openaire   +3 more sources

Synthesis of ubiquinones. Elongation of the heptaprenyl side-chain in ubiquinone-7

Journal of the Chemical Society, Perkin Transactions 1, 1978
Regio- and stereo-chemically selective transformation of the terminal trans-methyl group of the heptaprenyl side-chain in ubiquinone-7 (1a; n= 6) and its O-benzylated quinol (1b) into the trans-chloromethyl group and the coupling of the resulting compound (10b) with prenyl, geranyl, and farnesyl p-tolyl sulphones (14a, b, c), with subsequent reductive ...
Kaneyoshi Kato, Hiroshi Morimoto, Shinji Terao, Mitsuru Shiraishi   +3 more
openaire   +2 more sources

Conversion of ubiquinone-9 to ubiquinone-10 by use of the wittig reaction

Bulletin of the Academy of Sciences of the USSR Division of Chemical Science, 1987
1. Five- and seven-stage methods were developed for converting ubiquinone-9 and the dibenzyl ether of the corresponding hydroquinone to ubiquinone-10 by use of the Wittig reaction at the key stage; the overall yield was 2 and 17%, respectively. 2.
A. M. Moiseenkov, V. M. Zhulin, T. M. Filippova, E. A. Obol'nikova, G. I. Samokhvalov, A. B. Veselovskii   +5 more
openaire   +2 more sources

Ubiquinones: Stereochemistry and Biological Implications

Membrane Biochemistry, 1981
Proton NMR and 13C-NMR studies on the configuration of CoQn homologues show that the polyisoprenoid side-chain is in the all-trans configuration and confers a higher degree of rigidity to the quinones with respect to the acyl-chains of the phospholipids within the membrane bilayer.
C. A. Boicelli, C. Ramponi, L. Masotti, CASALI, Emanuela   +3 more
openaire   +3 more sources