Results 161 to 170 of about 30,210 (297)

Conformational Dynamics Modulate Activation of the Ubiquitin Conjugating Enzyme Ube2g2

ACS Omega, 2017
Pearl Magala, William E. Bocik, Ananya Majumdar, Joel R. Tolman   +3 more
doaj   +1 more source

MAZ-Mediated ubiquitin-conjugating enzyme E2C upregulation promotes breast cancer progression via the MAPK signaling pathway. [PDF]

Transl Oncol
Bai J, Deng M, Wu X, Xiong C, Wu H, Wang L, Qin J.   +6 more
europepmc   +1 more source

Role of high ubiquitin-conjugating enzyme E2 expression as a prognostic factor in nasopharyngeal carcinoma. [PDF]

Oncol Lett, 2022
Kao WC, Hsu SH, Lin CL, Lin CY, Chen SW, Chen YX, Chen CH, Lee SW, Tsao CJ, Huang WT, Chen SH, Hsiao SY.   +11 more
europepmc   +1 more source

Downregulation of Ubiquitin-conjugating Enzyme UBE2D3 Promotes Telomere Maintenance and Radioresistance of Eca-109 Human Esophageal Carcinoma Cells [PDF]

, 2016
Hui Yang, Lin Wu, Shaobo Ke, Wenbo Wang, Lei Yang, Xiaojia Gao, Hongyan Fang, Haijun Yu, Yahua Zhong, Conghua Xie, Fuxiang Zhou, Yunfeng Zhou   +11 more
openalex   +1 more source

Phocaeicola coprophilus‐Derived 6‐Methyluracil Attenuates Radiation‐Induced Intestinal Fibrosis by Suppressing the IDO1‐Kynurenine‐AHR Axis

Advanced Science, EarlyView.
IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang, Zhen Wang, Shuang Li, Chao Luo, Han Li, Shengjie Ma, Pai Wang, Heshi Liu, Lijun Sun, Yue Yin, Weizhen Zhang, Quan Wang   +11 more
wiley   +1 more source

UBE2O, a host ubiquitin-conjugating enzyme, is a key regulator of hepatitis B virus maturation and egress. [PDF]

J Biol Chem
Lubyova B, Tikalova E, Janovec V, Ryabchenko B, Krulova K, Kropacek V, Huerfano S, Hirsch I, Weber J.   +8 more
europepmc   +1 more source

African swine fever virus ubiquitin-conjugating enzyme pI215L inhibits IFN-I signaling pathway through STAT2 degradation. [PDF]

Front Microbiol, 2022
Riera E, García-Belmonte R, Madrid R, Pérez-Núñez D, Revilla Y.   +4 more
europepmc   +1 more source

Molecular Basis for Lysine Specificity in the Yeast Ubiquitin-Conjugating Enzyme Cdc34 [PDF]

, 2010
Martin C. Sadowski, Randy Suryadinata, Xianning Lai, Jörg Heierhorst, Boris Šarčević   +4 more
openalex   +1 more source

Potent and Selective IGF‐IIR‐Recruiting Bifunctional Molecules for Targeted Lysosomal Degradation of Extracellular and Membrane Proteins

Advanced Science, EarlyView.
Lysosome‐targeting chimeras (LYTACs) enable degradation of extracellular and membrane proteins via lysosomal trafficking. We report a novel IGF‐II mutant (Del1–7, Y27L) that selectively engages IGF‐IIR while avoiding IGF‐IR and IR‐A. mutIGF‐II–based LYTACs enhance target internalization and degradation and support a genetically encodable, all‐protein ...
Yuan Zhao, Yaxian Liao, Pengyun Li, Regina Stasser de Gonzalez, Xuankun Chen, Nicholas S. Nieto, Florence M. Brunel, Nick Cox, Joseph Stock, Matthew McHenry, Guangsen Fu, Penghsuan Huang, Wenxin Wu, Deqin Cai, Lingjun Li, Alexander N. Zaykov, Weiping Tang   +16 more
wiley   +1 more source

Comprehensive pan-cancer analysis reveals ubiquitin-conjugating enzyme 2T as a potential biomarker for prognosis and cancer immunity. [PDF]

Oncol Lett
Zhou Z, Chen YH, Xie AN, Li P.
europepmc   +1 more source