A human ubiquitin-conjugating enzyme homologous to yeast UBC8.
Ubiquitin-conjugating enzymes catalyze the covalent attachment of ubiquitin to cellular substrates. Here we describe the isolation of a novel ubiquitin-conjugating enzyme from human placenta and the cloning of the corresponding cDNA. DNA sequencing revealed that this gene, UbcH2, encodes a protein with significant sequence similarity to yeast UBC8.
Peter Kaiser +8 more
openalex +4 more sources
NMR chemical shift assignment of UEV domain of ubiquitin-conjugating enzyme E2 variant 3 lactate dehydrogenase (UEVLD). [PDF]
Vazquez JG +3 more
europepmc +2 more sources
The Ubiquitin-Conjugating Enzyme E2 O (UBE2O) and Its Therapeutic Potential in Human Leukemias and Solid Tumors. [PDF]
Maffeo B, Cilloni D.
europepmc +3 more sources
Ubiquitin conjugating enzyme E2 C (UBE2C) may play a dual role involved in the progression of thyroid carcinoma. [PDF]
Xiang C, Yan HC.
europepmc +3 more sources
UBE2J1 is the E2 ubiquitin-conjugating enzyme regulating androgen receptor degradation and antiandrogen resistance. [PDF]
Rodriguez Tirado C +19 more
europepmc +3 more sources
Prevalence of antibodies targeting ubiquitin-conjugating enzyme 2L3 and eukaryote translation elongation factor 1 α1 in Chinese Han and American Caucasian populations with type 1 diabetes. [PDF]
Qian L +6 more
europepmc +3 more sources
Targeting neddylation E2s: a novel therapeutic strategy in cancer
Ubiquitin-conjugating enzyme E2 M (UBE2M) and ubiquitin-conjugating enzyme E2 F (UBE2F) are the two NEDD8-conjugating enzymes of the neddylation pathway that take part in posttranslational modification and change the activity of target proteins.
Yi-Chao Zheng +6 more
doaj +1 more source

